ID   TX36D_CTEON             Reviewed;          25 AA.
AC   P85277;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 23.
DE   RecName: Full=U11-ctenitoxin-Co1b;
DE            Short=U11-CNTX-Co1b;
DE   AltName: Full=Neurotoxin Oc M9-7;
DE   Flags: Fragment;
OS   Ctenus ornatus (Brazilian spider) (Oligoctenus ornatus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC   Araneomorphae; Entelegynae; Lycosoidea; Ctenidae; Oligoctenus.
OX   NCBI_TaxID=406443;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND MASS
RP   SPECTROMETRY.
RC   TISSUE=Venom;
RA   Borges M.H., Oliveira C.F.B., Goncalves J.M., Rates B., Santos D.M.,
RA   Pimenta A.M.C., Cordeiro M.N., Richardson M.;
RL   Submitted (JUL-2007) to UniProtKB.
CC   -!- FUNCTION: Neurotoxin. {ECO:0000250|UniProtKB:P59367}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250|UniProtKB:P59367}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000269|Ref.1}.
CC   -!- DOMAIN: The presence of a 'disulfide through disulfide knot'
CC       structurally defines this protein as a knottin. {ECO:0000305}.
CC   -!- MASS SPECTROMETRY: Mass=3493.04; Mass_error=0.45; Method=Electrospray;
CC       Evidence={ECO:0000269|Ref.1};
CC   -!- SIMILARITY: Belongs to the neurotoxin 03 (Tx2) family. 06 subfamily.
CC       {ECO:0000305}.
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DR   AlphaFoldDB; P85277; -.
DR   ArachnoServer; AS000374; U11-ctenitoxin-Co1b (N-terminal fragment).
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   InterPro; IPR035285; CNTX.
DR   Pfam; PF17492; D_CNTX; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Knottin; Neurotoxin; Secreted;
KW   Toxin.
FT   CHAIN           1..>25
FT                   /note="U11-ctenitoxin-Co1b"
FT                   /id="PRO_0000302114"
FT   DISULFID        4..18
FT                   /evidence="ECO:0000305"
FT   DISULFID        11..22
FT                   /evidence="ECO:0000305"
FT   DISULFID        17..?
FT                   /evidence="ECO:0000305"
FT   DISULFID        24..?
FT                   /evidence="ECO:0000305"
FT   NON_TER         25
SQ   SEQUENCE   25 AA;  2691 MW;  CD61E40BCF473D68 CRC64;
     KAKCAEIDQD CKTSCDCCKG ACTCY