ID   TX3AB_DINAS             Reviewed;          23 AA.
AC   P0CF01;
DT   20-APR-2010, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 1.
DT   25-MAY-2022, entry version 18.
DE   RecName: Full=U1-poneritoxin-Da3b {ECO:0000303|PubMed:26805882};
DE            Short=U1-PONTX-Da3b {ECO:0000303|PubMed:26805882};
DE   AltName: Full=Dinoponeratoxin Da-2501 {ECO:0000303|PubMed:19879289};
DE   AltName: Full=Poneratoxin {ECO:0000305};
DE   Contains:
DE     RecName: Full=U1-poneritoxin-Da3a {ECO:0000303|PubMed:26805882};
DE              Short=U1-PONTX-Da3a {ECO:0000303|PubMed:26805882};
DE     AltName: Full=Dinoponeratoxin Da-1585 {ECO:0000303|PubMed:19879289};
OS   Dinoponera australis (Giant neotropical hunting ant).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Ponerinae; Ponerini; Dinoponera.
OX   NCBI_TaxID=609289;
RN   [1]
RP   PROTEIN SEQUENCE, MASS SPECTROMETRY, SYNTHESIS, AND SUBCELLULAR LOCATION.
RC   TISSUE=Venom;
RX   PubMed=19879289; DOI=10.1016/j.toxicon.2009.10.021;
RA   Johnson S.R., Copello J.A., Evans M.S., Suarez A.V.;
RT   "A biochemical characterization of the major peptides from the venom of the
RT   giant Neotropical hunting ant Dinoponera australis.";
RL   Toxicon 55:702-710(2010).
RN   [2]
RP   REVIEW, AND NOMENCLATURE.
RX   PubMed=26805882; DOI=10.3390/toxins8010030;
RA   Touchard A., Aili S.R., Fox E.G., Escoubas P., Orivel J., Nicholson G.M.,
RA   Dejean A.;
RT   "The biochemical toxin arsenal from ant venoms.";
RL   Toxins 8:1-28(2016).
CC   -!- FUNCTION: [U1-poneritoxin-Da3b]: May have antimicrobial properties,
CC       like most ant linear peptides. {ECO:0000305}.
CC   -!- FUNCTION: [U1-poneritoxin-Da3a]: May have antimicrobial properties,
CC       like most ant linear peptides. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:19879289}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC       {ECO:0000305|PubMed:19879289}.
CC   -!- MASS SPECTROMETRY: [U1-poneritoxin-Da3b]: Mass=2501.4;
CC       Method=Electrospray; Evidence={ECO:0000269|PubMed:19879289};
CC   -!- MASS SPECTROMETRY: [U1-poneritoxin-Da3a]: Mass=1584.9;
CC       Method=Electrospray; Evidence={ECO:0000269|PubMed:19879289};
CC   -!- SIMILARITY: Belongs to the non-disulfide-bridged peptide (NDBP)
CC       superfamily. Medium-length antimicrobial peptide (group 3) family.
CC       Ponericin-W subfamily. {ECO:0000305}.
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DR   AlphaFoldDB; P0CF01; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0098542; P:defense response to other organism; IEA:InterPro.
DR   InterPro; IPR012523; Antimicrobial_4.
DR   Pfam; PF08024; Antimicrobial_4; 1.
PE   1: Evidence at protein level;
KW   Antimicrobial; Direct protein sequencing; Secreted.
FT   PEPTIDE         1..23
FT                   /note="U1-poneritoxin-Da3b"
FT                   /evidence="ECO:0000269|PubMed:19879289"
FT                   /id="PRO_0000393344"
FT   PEPTIDE         9..23
FT                   /note="U1-poneritoxin-Da3a"
FT                   /evidence="ECO:0000269|PubMed:19879289"
FT                   /id="PRO_0000393345"
SQ   SEQUENCE   23 AA;  2503 MW;  D30E09983E13138E CRC64;
     FWGTLAKLAL KAVPAVMGMI KKE