TX41B_SCODE
ID TX41B_SCODE Reviewed; 67 AA.
AC P0DPV4;
DT 10-APR-2019, integrated into UniProtKB/Swiss-Prot.
DT 10-APR-2019, sequence version 1.
DT 25-MAY-2022, entry version 8.
DE RecName: Full=Kappa-scoloptoxin(04)-Ssd1b {ECO:0000305};
DE Short=Kappa-SLPTX(04)-Ssd1b {ECO:0000305};
DE AltName: Full=Toxin SSD410 {ECO:0000303|PubMed:23148443};
DE Flags: Precursor;
OS Scolopendra dehaani (Thai centipede) (Scolopendra subspinipes dehaani).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Scolopendromorpha; Scolopendridae; Scolopendra.
OX NCBI_TaxID=2609776;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 37-67, SUBCELLULAR
RP LOCATION, AND MASS SPECTROMETRY.
RC TISSUE=Venom, and Venom gland;
RX PubMed=23148443; DOI=10.1021/pr300881d;
RA Liu Z.C., Zhang R., Zhao F., Chen Z.M., Liu H.W., Wang Y.J., Jiang P.,
RA Zhang Y., Wu Y., Ding J.P., Lee W.H., Zhang Y.;
RT "Venomic and transcriptomic analysis of centipede Scolopendra subspinipes
RT dehaani.";
RL J. Proteome Res. 11:6197-6212(2012).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:23148443}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:23148443}.
CC -!- PTM: Contains 2 disulfide bonds. {ECO:0000305}.
CC -!- MASS SPECTROMETRY: Mass=3358.6; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:23148443};
CC -!- SIMILARITY: Belongs to the scoloptoxin-04 family. {ECO:0000305}.
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DR EMBL; KC144409; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; P0DPV4; -.
DR SMR; P0DPV4; -.
DR TCDB; 8.B.41.1.2; the centipede toxin (rhtx) family.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Cleavage on pair of basic residues; Direct protein sequencing;
KW Disulfide bond; Secreted; Signal; Toxin.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT PROPEP 25..36
FT /evidence="ECO:0000305|PubMed:23148443"
FT /id="PRO_0000446712"
FT CHAIN 37..67
FT /note="Kappa-scoloptoxin(04)-Ssd1b"
FT /evidence="ECO:0000269|PubMed:23148443"
FT /id="PRO_0000446713"
SQ SEQUENCE 67 AA; 7475 MW; 91E33E5B11127EC0 CRC64;
MKKTCVVSVF LVLLLLKFHD LSMGEEISPL KKVARREDNL VLSCAEFPCP EGYICDTASQ
KCRPGTD