TX42A_SCODE
ID TX42A_SCODE Reviewed; 66 AA.
AC P0DPX1;
DT 10-APR-2019, integrated into UniProtKB/Swiss-Prot.
DT 10-APR-2019, sequence version 1.
DT 25-MAY-2022, entry version 6.
DE RecName: Full=U-scoloptoxin(04)-Ssd2a {ECO:0000305|PubMed:24847043};
DE Short=U-SLPTX(04)-Ssd2a {ECO:0000305|PubMed:24847043};
DE AltName: Full=Toxin SSD416 {ECO:0000303|PubMed:23148443};
DE Flags: Precursor;
OS Scolopendra dehaani (Thai centipede) (Scolopendra subspinipes dehaani).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Scolopendromorpha; Scolopendridae; Scolopendra.
OX NCBI_TaxID=2609776;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Venom gland;
RX PubMed=23148443; DOI=10.1021/pr300881d;
RA Liu Z.C., Zhang R., Zhao F., Chen Z.M., Liu H.W., Wang Y.J., Jiang P.,
RA Zhang Y., Wu Y., Ding J.P., Lee W.H., Zhang Y.;
RT "Venomic and transcriptomic analysis of centipede Scolopendra subspinipes
RT dehaani.";
RL J. Proteome Res. 11:6197-6212(2012).
RN [2]
RP NOMENCLATURE.
RX PubMed=24847043; DOI=10.1093/molbev/msu162;
RA Undheim E.A., Jones A., Clauser K.R., Holland J.W., Pineda S.S., King G.F.,
RA Fry B.G.;
RT "Clawing through evolution: toxin diversification and convergence in the
RT ancient lineage Chilopoda (centipedes).";
RL Mol. Biol. Evol. 31:2124-2148(2014).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:24847043}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:24847043}.
CC -!- PTM: Contains 2 disulfide bonds. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the scoloptoxin-04 family. {ECO:0000305}.
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DR EMBL; KC144415; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; P0DPX1; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Disulfide bond; Secreted; Signal; Toxin.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..66
FT /note="U-scoloptoxin(04)-Ssd2a"
FT /evidence="ECO:0000305"
FT /id="PRO_0000446716"
SQ SEQUENCE 66 AA; 7509 MW; B0F7ADEF7C4E9DC4 CRC64;
MKAIYILSVL LLMMLPILSR FATSEGAAQH VEPIQKIRVE QNDCTRGIRC PRGHYCDPGL
RQCLPR