ACBP3_CAEEL
ID ACBP3_CAEEL Reviewed; 116 AA.
AC Q20507;
DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT 11-APR-2003, sequence version 2.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Acyl-CoA-binding protein homolog 3;
DE Short=ACBP-3;
GN Name=acbp-3; ORFNames=F47B10.7;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Binds medium- and long-chain acyl-CoA esters with very high
CC affinity and may function as an intracellular carrier of acyl-CoA
CC esters. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ACBP family. {ECO:0000305}.
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DR EMBL; Z68004; CAA91987.2; -; Genomic_DNA.
DR PIR; T22338; T22338.
DR RefSeq; NP_509822.2; NM_077421.5.
DR AlphaFoldDB; Q20507; -.
DR SMR; Q20507; -.
DR BioGRID; 46192; 16.
DR STRING; 6239.F47B10.7; -.
DR EPD; Q20507; -.
DR PaxDb; Q20507; -.
DR PeptideAtlas; Q20507; -.
DR EnsemblMetazoa; F47B10.7.1; F47B10.7.1; WBGene00009818.
DR GeneID; 181281; -.
DR KEGG; cel:CELE_F47B10.7; -.
DR UCSC; F47B10.7; c. elegans.
DR CTD; 181281; -.
DR WormBase; F47B10.7; CE32423; WBGene00009818; acbp-3.
DR eggNOG; KOG0817; Eukaryota.
DR HOGENOM; CLU_118853_1_0_1; -.
DR InParanoid; Q20507; -.
DR OMA; RKKWDAW; -.
DR OrthoDB; 1546859at2759; -.
DR PhylomeDB; Q20507; -.
DR Reactome; R-CEL-390918; Peroxisomal lipid metabolism.
DR PRO; PR:Q20507; -.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00009818; Expressed in larva and 3 other tissues.
DR GO; GO:0000062; F:fatty-acyl-CoA binding; IBA:GO_Central.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR GO; GO:0019915; P:lipid storage; IMP:WormBase.
DR CDD; cd00435; ACBP; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR InterPro; IPR022408; Acyl-CoA-binding_prot_CS.
DR InterPro; IPR000582; Acyl-CoA-binding_protein.
DR InterPro; IPR035984; Acyl-CoA-binding_sf.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR Pfam; PF00887; ACBP; 1.
DR PRINTS; PR00689; ACOABINDINGP.
DR SUPFAM; SSF47027; SSF47027; 1.
DR PROSITE; PS00880; ACB_1; 1.
DR PROSITE; PS51228; ACB_2; 1.
PE 3: Inferred from homology;
KW Lipid-binding; Reference proteome; Transport.
FT CHAIN 1..116
FT /note="Acyl-CoA-binding protein homolog 3"
FT /id="PRO_0000214026"
FT DOMAIN 3..92
FT /note="ACB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00573"
FT BINDING 34..38
FT /ligand="an acyl-CoA"
FT /ligand_id="ChEBI:CHEBI:58342"
FT /evidence="ECO:0000250"
FT BINDING 60
FT /ligand="an acyl-CoA"
FT /ligand_id="ChEBI:CHEBI:58342"
FT /evidence="ECO:0000250"
FT BINDING 79
FT /ligand="an acyl-CoA"
FT /ligand_id="ChEBI:CHEBI:58342"
FT /evidence="ECO:0000250"
SQ SEQUENCE 116 AA; 13174 MW; D2BDE14AC1784FF2 CRC64;
MSLQEKFDAA VEIIQKLPKT GPVATSNDQK LTFYSLFKQA SIGDVNTDRP GIFSIIERKK
WDSWKELEGV SQDEAKERYI KALNDMFDKI AEELDVAAWL EQIDPVIKTN LALIGK
