TX820_LYCSI
ID TX820_LYCSI Reviewed; 77 AA.
AC B6DCZ1;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 25-NOV-2008, sequence version 1.
DT 25-MAY-2022, entry version 16.
DE RecName: Full=U8-lycotoxin-Ls1k;
DE AltName: Full=Toxin-like structure LSTX-H20;
DE Flags: Precursor;
OS Lycosa singoriensis (Wolf spider) (Aranea singoriensis).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC Araneomorphae; Entelegynae; Lycosoidea; Lycosidae; Lycosa.
OX NCBI_TaxID=434756;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Venom gland;
RX PubMed=19875276; DOI=10.1016/j.zool.2009.04.001;
RA Zhang Y., Chen J., Tang X., Wang F., Jiang L., Xiong X., Wang M., Rong M.,
RA Liu Z., Liang S.;
RT "Transcriptome analysis of the venom glands of the Chinese wolf spider
RT Lycosa singoriensis.";
RL Zoology 113:10-18(2010).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC -!- PTM: Contains 4 disulfide bonds. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the neurotoxin 19 (CSTX) family. 08 (U8-Lctx)
CC subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EU926075; ACI41407.1; -; mRNA.
DR EMBL; FM864079; CAS03676.1; -; mRNA.
DR AlphaFoldDB; B6DCZ1; -.
DR SMR; B6DCZ1; -.
DR ArachnoServer; AS001014; U8-lycotoxin-Ls1k.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR InterPro; IPR019553; Spider_toxin_CSTX_knottin.
DR Pfam; PF10530; Toxin_35; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Secreted; Signal; Toxin.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT PROPEP 21..26
FT /evidence="ECO:0000250"
FT /id="PRO_0000401801"
FT CHAIN 27..77
FT /note="U8-lycotoxin-Ls1k"
FT /id="PRO_0000401802"
SQ SEQUENCE 77 AA; 8609 MW; 69CB4581CA1BEE4C CRC64;
MKLIIFTGLI LFPIVSLIEA QAKNEKACLP QYQVCTDAPG NCCSNLICDC YGRYKNGARI
GRNCFCLQKG VLYKKEN