ID   TX85A_SCOAL             Reviewed;         122 AA.
AC   A0A023W168;
DT   10-APR-2019, integrated into UniProtKB/Swiss-Prot.
DT   09-JUL-2014, sequence version 1.
DT   25-MAY-2022, entry version 9.
DE   RecName: Full=U-scoloptoxin-Sa5a {ECO:0000305};
DE            Short=U-SLPTX-Sa5a {ECO:0000305};
DE   AltName: Full=U-scoloptoxin-Er5-like {ECO:0000312|EMBL:AHY22615.1};
DE            Short=U-SLPTX-Er5-like {ECO:0000312|EMBL:AHY22615.1};
DE   Flags: Precursor;
OS   Scolopendra alternans (Florida Keys giant centipede).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC   Pleurostigmophora; Scolopendromorpha; Scolopendridae; Scolopendra.
OX   NCBI_TaxID=1329349;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RX   PubMed=24602922; DOI=10.1016/j.jprot.2014.02.024;
RA   Undheim E.A., Sunagar K., Hamilton B.R., Jones A., Venter D.J., Fry B.G.,
RA   King G.F.;
RT   "Multifunctional warheads: diversification of the toxin arsenal of
RT   centipedes via novel multidomain transcripts.";
RL   J. Proteomics 102:1-10(2014).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:24602922}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC       {ECO:0000305|PubMed:24602922}.
CC   -!- SIMILARITY: Belongs to the scoloptoxin-08 family. {ECO:0000305}.
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DR   EMBL; KF130764; AHY22615.1; -; mRNA.
DR   AlphaFoldDB; A0A023W168; -.
DR   SMR; A0A023W168; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Cleavage on pair of basic residues; Repeat; Secreted; Signal; Toxin.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   PROPEP          26..86
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000446732"
FT   PEPTIDE         87..104
FT                   /note="U-scoloptoxin-Sa5a"
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_5001524653"
FT   PROPEP          105..122
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000446733"
FT   REPEAT          40..46
FT                   /note="RLWRNWE 1"
FT                   /evidence="ECO:0000305|PubMed:24602922"
FT   REPEAT          56..62
FT                   /note="RLWRNWE 2"
FT                   /evidence="ECO:0000305|PubMed:24602922"
FT   REPEAT          72..78
FT                   /note="RLWRNWE 3"
FT                   /evidence="ECO:0000305|PubMed:24602922"
SQ   SEQUENCE   122 AA;  15405 MW;  F6EE1DA893266907 CRC64;
     MIFSRIMRGL LCLCLVLTVF ELINGSDEFE HQDSLHLVKR LWRNWEEDQQ KDREKRLWRN
     WEEEEQKDRE KRLWRNWEEE EQKEKRNLPE LKYEMEKNQE VPQLKRKRGI LEKIWIPNEI
     GR