ID   TX8A_ANEVI              Reviewed;          79 AA.
AC   P0DMZ3;
DT   16-SEP-2015, integrated into UniProtKB/Swiss-Prot.
DT   16-SEP-2015, sequence version 1.
DT   03-AUG-2022, entry version 9.
DE   RecName: Full=U-actitoxin-Avd8a {ECO:0000303|PubMed:22683676};
DE            Short=U-AITX-Avd8a {ECO:0000303|PubMed:22683676};
DE   AltName: Full=Avtx-1 {ECO:0000303|PubMed:21281459};
DE   Flags: Precursor;
OS   Anemonia viridis (Snakelocks anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Actiniidae; Anemonia.
OX   NCBI_TaxID=51769;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=19627569; DOI=10.1186/1471-2164-10-333;
RA   Sabourault C., Ganot P., Deleury E., Allemand D., Furla P.;
RT   "Comprehensive EST analysis of the symbiotic sea anemone, Anemonia
RT   viridis.";
RL   BMC Genomics 10:333-333(2009).
RN   [2]
RP   NOMENCLATURE.
RX   PubMed=21281459; DOI=10.1186/1471-2164-12-88;
RA   Kozlov S., Grishin E.;
RT   "The mining of toxin-like polypeptides from EST database by single residue
RT   distribution analysis.";
RL   BMC Genomics 12:88-88(2011).
RN   [3]
RP   NOMENCLATURE.
RX   PubMed=22683676; DOI=10.1016/j.toxicon.2012.05.020;
RA   Oliveira J.S., Fuentes-Silva D., King G.F.;
RT   "Development of a rational nomenclature for naming peptide and protein
RT   toxins from sea anemones.";
RL   Toxicon 60:539-550(2012).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}. Nematocyst {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the sea anemone 8 toxin family. {ECO:0000305}.
CC   -!- CAUTION: Opinions are divided on whether Anemonia viridis (Forsskal,
CC       1775) and Anemonia sulcata (Pennant, 1777) are separate species.
CC       {ECO:0000305}.
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DR   EMBL; FK752567; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FK758080; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FK726322; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FK721446; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FK753446; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FK739257; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FK758248; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FK746508; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FK720062; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FK734697; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FK744639; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FK750058; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FK757190; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; P0DMZ3; -.
DR   SMR; P0DMZ3; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042151; C:nematocyst; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Nematocyst; Secreted; Signal; Toxin.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   PROPEP          20..36
FT                   /evidence="ECO:0000305|PubMed:21281459"
FT                   /id="PRO_0000433703"
FT   CHAIN           37..79
FT                   /note="U-actitoxin-Avd8a"
FT                   /id="PRO_0000433704"
SQ   SEQUENCE   79 AA;  8792 MW;  CD757EA02C703BA6 CRC64;
     MKSLVIVFVV LLGVAMISAN EEELLAILQD QRNDARGGCM NRYKSNICGT LVTPMNCIAP
     RTRMGKFARK FCQFMCGIC