TX93A_SCOMO
ID TX93A_SCOMO Reviewed; 74 AA.
AC A0A023W0V6;
DT 10-APR-2019, integrated into UniProtKB/Swiss-Prot.
DT 09-JUL-2014, sequence version 1.
DT 25-MAY-2022, entry version 10.
DE RecName: Full=U-scoloptoxin(09)-Sm3a {ECO:0000303|PubMed:24847043};
DE Short=U-SLPTX(09)-Sm3a {ECO:0000303|PubMed:24847043};
DE AltName: Full=U-SLPTX-Sm3a {ECO:0000312|EMBL:AHY22604.1};
DE Flags: Precursor;
OS Scolopendra morsitans (Tanzanian blue ringleg centipede).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Scolopendromorpha; Scolopendridae; Scolopendra.
OX NCBI_TaxID=943129;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Venom gland;
RX PubMed=24602922; DOI=10.1016/j.jprot.2014.02.024;
RA Undheim E.A., Sunagar K., Hamilton B.R., Jones A., Venter D.J., Fry B.G.,
RA King G.F.;
RT "Multifunctional warheads: diversification of the toxin arsenal of
RT centipedes via novel multidomain transcripts.";
RL J. Proteomics 102:1-10(2014).
RN [2]
RP NOMENCLATURE.
RX PubMed=24847043; DOI=10.1093/molbev/msu162;
RA Undheim E.A., Jones A., Clauser K.R., Holland J.W., Pineda S.S., King G.F.,
RA Fry B.G.;
RT "Clawing through evolution: toxin diversification and convergence in the
RT ancient lineage Chilopoda (centipedes).";
RL Mol. Biol. Evol. 31:2124-2148(2014).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:24602922}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:24602922}.
CC -!- PTM: Contains 3 disulfide bonds. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the scoloptoxin-09 family. {ECO:0000305}.
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DR EMBL; KF130753; AHY22604.1; -; mRNA.
DR AlphaFoldDB; A0A023W0V6; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Disulfide bond; Secreted; Signal; Toxin.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..74
FT /note="U-scoloptoxin(09)-Sm3a"
FT /evidence="ECO:0000305"
FT /id="PRO_5001524790"
SQ SEQUENCE 74 AA; 8023 MW; 77A6DA30A7767F0F CRC64;
MNANSIFLCF FIMLIGCTLT HSCPSGCYCD QVDGNKCRPE EGTNPHLCLG KYCKTPDSSS
VITGNQDEKT QAKG