ID   TXB2A_SCOAL             Reviewed;         229 AA.
AC   P0DPZ6;
DT   10-APR-2019, integrated into UniProtKB/Swiss-Prot.
DT   10-APR-2019, sequence version 1.
DT   25-MAY-2022, entry version 5.
DE   RecName: Full=U-scoloptoxin(11)-Sa2a {ECO:0000303|PubMed:24847043};
DE            Short=U-SLPTX(11)-Sa2a {ECO:0000303|PubMed:24847043};
DE   Flags: Precursor;
OS   Scolopendra alternans (Florida Keys giant centipede).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC   Pleurostigmophora; Scolopendromorpha; Scolopendridae; Scolopendra.
OX   NCBI_TaxID=1329349;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND NOMENCLATURE.
RC   TISSUE=Venom gland;
RX   PubMed=24847043; DOI=10.1093/molbev/msu162;
RA   Undheim E.A., Jones A., Clauser K.R., Holland J.W., Pineda S.S., King G.F.,
RA   Fry B.G.;
RT   "Clawing through evolution: toxin diversification and convergence in the
RT   ancient lineage Chilopoda (centipedes).";
RL   Mol. Biol. Evol. 31:2124-2148(2014).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:24847043}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC       {ECO:0000305|PubMed:24847043}.
CC   -!- PTM: Contains 8 disulfide bonds. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the scoloptoxin-11 family. {ECO:0000305}.
CC   -!- WEB RESOURCE: Name=National Center for Biotechnology Information
CC       (NCBI);
CC       URL="https://www.ncbi.nlm.nih.gov/nuccore/GASK01000037";
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DR   AlphaFoldDB; P0DPZ6; -.
DR   SMR; P0DPZ6; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Secreted; Signal; Toxin.
FT   SIGNAL          1..14
FT                   /evidence="ECO:0000255"
FT   CHAIN           15..229
FT                   /note="U-scoloptoxin(11)-Sa2a"
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000446766"
SQ   SEQUENCE   229 AA;  26054 MW;  59D4E9AC38B90BA7 CRC64;
     MFLLLGFIFL AAEAFNFQLR NAMESKELFK KRELTTEDEL ATCNSDSICG YLQNNVKGTN
     YVPLCACPGE IRCPRSWDSN DGKSLTRGNE QFKFCSSSPQ DLHDCKANEL VFTAVYEYLS
     NVNPKKFAAY TGNIHCKCPD EFAYNLFNRT KKATADREIH TVYFSCQEYN ICGSNDTCHI
     ISESPDNFHI YKICNCDNGL QCSDNPDAAF KTVKLEQGPL FNQYSMRCQ