ID   TXBA_ANDCR              Reviewed;          26 AA.
AC   P0C2A2;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 21.
DE   RecName: Full=Toxin b subunit alpha;
DE   Flags: Fragment;
OS   Androctonus crassicauda (Arabian fat-tailed scorpion).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Scorpiones; Buthida; Buthoidea; Buthidae; Androctonus.
OX   NCBI_TaxID=122909;
RN   [1]
RP   PROTEIN SEQUENCE, AND SUBUNIT.
RC   TISSUE=Venom;
RX   PubMed=16762386; DOI=10.1016/j.toxicon.2006.04.003;
RA   Caliskan F., Garcia B.I., Coronas F.I.V., Batista C.V.F., Zamudio F.Z.,
RA   Possani L.D.;
RT   "Characterization of venom components from the scorpion Androctonus
RT   crassicauda of Turkey: peptides and genes.";
RL   Toxicon 48:12-22(2006).
CC   -!- FUNCTION: Binds to sodium channels (Nav) and affects the channel
CC       activation process. {ECO:0000250}.
CC   -!- SUBUNIT: Toxin b is a heterodimer composed of toxin alpha and toxin
CC       beta. {ECO:0000269|PubMed:16762386}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; P0C2A2; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0017080; F:sodium channel regulator activity; IEA:UniProtKB-KW.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Ion channel impairing toxin; Neurotoxin;
KW   Secreted; Toxin; Voltage-gated sodium channel impairing toxin.
FT   CHAIN           1..>26
FT                   /note="Toxin b subunit alpha"
FT                   /id="PRO_0000271329"
FT   NON_TER         26
SQ   SEQUENCE   26 AA;  3052 MW;  0A989684F24CB40F CRC64;
     DDLHPFNENN MYYGCKGLSN SNKFED