TXC2B_CUPSA
ID TXC2B_CUPSA Reviewed; 35 AA.
AC B3EWT7;
DT 06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2013, sequence version 1.
DT 25-MAY-2022, entry version 13.
DE RecName: Full=Cupiennin-2b {ECO:0000303|PubMed:22672445};
DE Short=Cu-2b {ECO:0000303|PubMed:22672445};
OS Cupiennius salei (American wandering spider).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC Araneomorphae; Entelegynae; Lycosoidea; Ctenidae; Cupiennius.
OX NCBI_TaxID=6928;
RN [1]
RP PROTEIN SEQUENCE, MASS SPECTROMETRY, AND AMIDATION AT GLN-35.
RC TISSUE=Venom;
RX PubMed=22672445; DOI=10.1111/j.1742-4658.2012.08650.x;
RA Trachsel C., Siegemund D., Kampfer U., Kopp L.S., Buhr C., Grossmann J.,
RA Luthi C., Cunningham M., Nentwig W., Kuhn-Nentwig L., Schurch S.,
RA Schaller J.;
RT "Multicomponent venom of the spider Cupiennius salei: a bioanalytical
RT investigation applying different strategies.";
RL FEBS J. 279:2683-2694(2012).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:22672445}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:22672445}.
CC -!- MASS SPECTROMETRY: Mass=3726.255; Method=Electrospray;
CC Evidence={ECO:0000269|PubMed:22672445};
CC -!- SIMILARITY: Belongs to the cationic peptide 04 (cupiennin) family. 02
CC subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; B3EWT7; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Secreted; Toxin.
FT PEPTIDE 1..35
FT /note="Cupiennin-2b"
FT /evidence="ECO:0000269|PubMed:22672445"
FT /id="PRO_0000421194"
FT MOD_RES 35
FT /note="Glutamine amide"
FT /evidence="ECO:0000269|PubMed:22672445"
SQ SEQUENCE 35 AA; 3730 MW; 275EBA19B0F06097 CRC64;
AFGTILKALA KIAAKVVKKL ATKPGATYML KQNLQ