TXL1A_SCOMO
ID TXL1A_SCOMO Reviewed; 71 AA.
AC P0DQF2;
DT 10-APR-2019, integrated into UniProtKB/Swiss-Prot.
DT 10-APR-2019, sequence version 1.
DT 25-MAY-2022, entry version 8.
DE RecName: Full=U-scoloptoxin(21)-Sm1a {ECO:0000303|PubMed:24847043};
DE Short=U-SLPTX(21)-Sm1a {ECO:0000303|PubMed:24847043};
DE Flags: Precursor;
OS Scolopendra morsitans (Tanzanian blue ringleg centipede).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Scolopendromorpha; Scolopendridae; Scolopendra.
OX NCBI_TaxID=943129;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND NOMENCLATURE.
RC TISSUE=Venom gland;
RX PubMed=24847043; DOI=10.1093/molbev/msu162;
RA Undheim E.A., Jones A., Clauser K.R., Holland J.W., Pineda S.S., King G.F.,
RA Fry B.G.;
RT "Clawing through evolution: toxin diversification and convergence in the
RT ancient lineage Chilopoda (centipedes).";
RL Mol. Biol. Evol. 31:2124-2148(2014).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:24847043}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:24847043}.
CC -!- SIMILARITY: Belongs to the scoloptoxin-21 family. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=National Center for Biotechnology Information
CC (NCBI);
CC URL="https://www.ncbi.nlm.nih.gov/nuccore/GASH01000171";
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DR AlphaFoldDB; P0DQF2; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Secreted; Signal; Toxin.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..71
FT /note="U-scoloptoxin(21)-Sm1a"
FT /evidence="ECO:0000305"
FT /id="PRO_0000446829"
FT REGION 45..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..71
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 71 AA; 7710 MW; EA6FB6110B94EB3F CRC64;
MKSVIFALFL VYLLIVRAAE ANENIGLGLD RGSSGTIAAK QQMGIELAND PNGPGRRRRA
PAENEDFLKH S