ID   TXP10_PLETR             Reviewed;          49 AA.
AC   P36990;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=U3-plectoxin-Pt1a;
DE            Short=U3-PLTX-Pt1a;
DE   AltName: Full=Plectoxin X;
DE            Short=PLT-X;
DE            Short=PLTX;
DE   AltName: Full=Plectoxin-10;
OS   Plectreurys tristis (Spider) (Plectreurys bispinosus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC   Araneomorphae; Haplogynae; Pholcoidea; Plectreuridae; Plectreurys.
OX   NCBI_TaxID=33319;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Venom;
RX   PubMed=8157635; DOI=10.1016/s0021-9258(19)78096-x;
RA   Quistad G.B., Skinner W.S.;
RT   "Isolation and sequencing of insecticidal peptides from the primitive
RT   hunting spider, Plectreurys tristis (Simon).";
RL   J. Biol. Chem. 269:11098-11101(1994).
CC   -!- FUNCTION: Potent toxin that may paralyze and/or kill insect pests such
CC       as H.virescens (lepidoptera), S.exigua (beet armyworm) and M.sexta
CC       (tobacco hornworm).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- DOMAIN: The presence of a 'disulfide through disulfide knot'
CC       structurally defines this protein as a knottin. {ECO:0000305}.
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DR   PIR; H53613; H53613.
DR   AlphaFoldDB; P36990; -.
DR   SMR; P36990; -.
DR   ArachnoServer; AS000391; U3-plectoxin-Pt1a.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Knottin; Neurotoxin; Secreted;
KW   Toxin.
FT   CHAIN           1..49
FT                   /note="U3-plectoxin-Pt1a"
FT                   /id="PRO_0000087662"
FT   DISULFID        2..16
FT                   /evidence="ECO:0000305"
FT   DISULFID        9..30
FT                   /evidence="ECO:0000305"
FT   DISULFID        15..41
FT                   /evidence="ECO:0000305"
FT   DISULFID        32..39
FT                   /evidence="ECO:0000305"
FT   DISULFID        45..49
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   49 AA;  5140 MW;  86294DF6DDDB3597 CRC64;
     GCKGFLVKCD SNSECCKTAI VKGKKKQLSC LCGAWGAGCS CSFRCGNRC