ID   C71A6_NEPRA             Reviewed;         511 AA.
AC   O04164;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Cytochrome P450 71A6;
DE            EC=1.14.-.-;
DE   Flags: Fragment;
GN   Name=CYP71A6;
OS   Nepeta racemosa (Catmint) (Raceme catnip).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Nepetinae;
OC   Nepeta.
OX   NCBI_TaxID=54731;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Leaf;
RX   PubMed=9106511; DOI=10.1023/a:1005706609510;
RA   Clark I.M., Forde B.G., Hallahan D.L.;
RT   "Spatially distinct expression of two new cytochrome P450s in leaves of
RT   Nepeta racemosa: identification of a trichome-specific isoform.";
RL   Plant Mol. Biol. 33:875-885(1997).
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000250|UniProtKB:P04798};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR   EMBL; Y09424; CAA70576.1; -; mRNA.
DR   AlphaFoldDB; O04164; -.
DR   SMR; O04164; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   Gene3D; 1.10.630.10; -; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; SSF48264; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Heme; Iron; Membrane; Metal-binding; Monooxygenase;
KW   Oxidoreductase; Transmembrane; Transmembrane helix.
FT   CHAIN           <1..511
FT                   /note="Cytochrome P450 71A6"
FT                   /id="PRO_0000052060"
FT   TRANSMEM        <1..15
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   BINDING         450
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000250|UniProtKB:P04798"
FT   CARBOHYD        90
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        96
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        167
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   NON_TER         1
SQ   SEQUENCE   511 AA;  57955 MW;  EEFC238BD8112432 CRC64;
     ILIALLCTLP FLFFLKKWRR SYSGKTPPPS PPKLPVLGNL HQLGTFPHRS LQSLSRRYGP
     VMQLHFGSVP VLVASSPEAA REIMKNQDLN FSNRPNLSIP RRLLYDNHDV AFAPYGEYWR
     QIRSICVLQL LSNKRVQSFR RVREEETSIM VEKIMQLQKT TPTAAVNLTD LLTCLTNDVF
     CRIALGKKYG GTTTGDGEYH VRSLKKNLAE FYVLLGISPL WEYIPWLEWT RRFDGVDRRI
     EEVSRTFDEF LGKVIQEHRV RDKREDTTVV GDTVGLDFVD LLLQFQRENE RSSSPVDDLT
     IKAVILDMFL AGTDTTVTAL EWALSELIKN PRAMKILQKE VRGVAGSKGE IEESDLEKMP
     YLKAVMKESL RLHAPVPLLV PRESTRDTKV LGYDVASGTR VLINCWAIGR DSSVWEESET
     FLPERFLETS IDYRGMHFEL IPFGSGRRGC PGATFAAAID ELALATLVHK FDFKLPNGVR
     VEDLDMSEGS GFTIHKKFPL LVVPTPHACT S