ID   TXTR3_LASSB             Reviewed;         116 AA.
AC   A3F7X2;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 17.
DE   RecName: Full=U3-theraphotoxin-Lsp1a;
DE            Short=U3-TRTX-Lsp1a;
DE   AltName: Full=LTx5;
DE   Flags: Precursor;
OS   Lasiodora sp. (strain IBSP 8539) (Brazilian salmon pink birdeater)
OS   (Brazilian salmon pink tarantula).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC   Mygalomorphae; Theraphosidae; Lasiodora; unclassified Lasiodora.
OX   NCBI_TaxID=300858;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RA   Castro I.M., Vieira A.L.G., Kalapothakis E.;
RT   "Screening of a Lasiodora sp. expression library and molecular cloning of
RT   Lasiodora sp. toxins in expression vectors.";
RL   Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- PTM: Contains 3 disulfide bonds. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the neurotoxin 25 family. F7 subfamily.
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DR   EMBL; EF219062; ABN13624.1; -; mRNA.
DR   AlphaFoldDB; A3F7X2; -.
DR   ArachnoServer; AS000719; U3-theraphotoxin-Lsp1a.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Secreted; Signal; Toxin.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   PROPEP          18..50
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000388747"
FT   CHAIN           51..116
FT                   /note="U3-theraphotoxin-Lsp1a"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000388748"
SQ   SEQUENCE   116 AA;  12908 MW;  ADCDA76682B49FFF CRC64;
     MKLSTFIIMI SLAVALATWP SEHIEGSDSE TKLNVELGPY ALADRAEKGK DDSLNKGEPC
     QFHCECRGAS VLCEAVYGTR SPMYKCMIKR LPISVLDIMY QAERALEKLA SSFRCE