ID   TXV2_PHONI              Reviewed;          20 AA.
AC   Q9TWR5;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=U27-ctenitoxin-Pn1a;
DE            Short=U27-CNTX-Pn1a;
DE   AltName: Full=Toxin PnV2;
DE   Flags: Fragment;
OS   Phoneutria nigriventer (Brazilian armed spider) (Ctenus nigriventer).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC   Araneomorphae; Entelegynae; Lycosoidea; Ctenidae; Phoneutria.
OX   NCBI_TaxID=6918;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Venom;
RX   PubMed=8216354; DOI=10.1016/0006-2952(93)90676-n;
RA   Bento A.C., Novello J.C., Marangoni S., Antunes E., Giglio J.R.,
RA   Oliveira B., de Nucci G.;
RT   "Identification of a new vascular smooth muscle contracting polypeptide in
RT   Phoneutria nigriventer spider venom.";
RL   Biochem. Pharmacol. 46:1092-1095(1993).
CC   -!- FUNCTION: Has a vascular smooth muscle contracting activity. Causes
CC       short-lived contractions of both arterial and venous rabbit vessels.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- PTM: Contains 4 disulfide bonds. {ECO:0000305}.
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DR   AlphaFoldDB; Q9TWR5; -.
DR   ArachnoServer; AS000421; U27-ctenitoxin-Pn1a.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Secreted; Toxin.
FT   CHAIN           1..>20
FT                   /note="U27-ctenitoxin-Pn1a"
FT                   /id="PRO_0000087646"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         20
SQ   SEQUENCE   20 AA;  2176 MW;  F28C3D81D983BCA5 CRC64;
     LAKRADICQP GKTSQRACET