ID   TY4_ASCTR               Reviewed;           9 AA.
AC   P84822;
DT   02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   02-MAY-2006, sequence version 1.
DT   11-DEC-2019, entry version 16.
DE   RecName: Full=Tryptophyllin-4;
OS   Ascaphus truei (Coastal tailed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Ascaphidae; Ascaphus.
OX   NCBI_TaxID=8439;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND MASS
RP   SPECTROMETRY.
RC   TISSUE=Skin secretion {ECO:0000269|PubMed:15922344};
RX   PubMed=15922344; DOI=10.1016/j.ygcen.2005.04.006;
RA   Conlon J.M., Jouenne T., Cosette P., Cosquer D., Vaudry H., Taylor C.K.,
RA   Abel P.W.;
RT   "Bradykinin-related peptides and tryptophyllins in the skin secretions of
RT   the most primitive extant frog, Ascaphus truei.";
RL   Gen. Comp. Endocrinol. 143:193-199(2005).
CC   -!- FUNCTION: Putative defense peptide.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15922344}.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin glands.
CC       {ECO:0000269|PubMed:15922344}.
CC   -!- MASS SPECTROMETRY: Mass=1184.6; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:15922344};
CC   -!- SIMILARITY: Belongs to the frog skin active peptide (FSAP) family.
CC       Tryptophillin subfamily. {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR   GO; GO:0006952; P:defense response; IEP:UniProtKB.
PE   1: Evidence at protein level;
KW   Amphibian defense peptide; Direct protein sequencing; Secreted.
FT   PEPTIDE         1..9
FT                   /note="Tryptophyllin-4"
FT                   /id="PRO_0000233927"
SQ   SEQUENCE   9 AA;  1185 MW;  27C27AB36771B417 CRC64;
     EPRTPWDWV