ID   TYBA_CYPCA              Reviewed;          46 AA.
AC   Q9I955;
DT   11-FEB-2002, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Thymosin beta-a;
OS   Cyprinus carpio (Common carp).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Cyprininae; Cyprinus.
OX   NCBI_TaxID=7962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Fujiki K., Nakao M., Shin D., Yano T.;
RT   "Molecular cloning of carp (Cyprinus carpio) thymosin beta a.";
RL   Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the organization of the
CC       cytoskeleton. Binds to and sequesters actin monomers (G actin) and
CC       therefore inhibits actin polymerization (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the thymosin beta family. {ECO:0000305}.
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DR   EMBL; AB028456; BAA96492.1; -; mRNA.
DR   RefSeq; XP_018939378.1; XM_019083833.1.
DR   AlphaFoldDB; Q9I955; -.
DR   SMR; Q9I955; -.
DR   Ensembl; ENSCCRT00000070702; ENSCCRP00000065231; ENSCCRG00000035120.
DR   Ensembl; ENSCCRT00010031614; ENSCCRP00010028822; ENSCCRG00010012315.
DR   Ensembl; ENSCCRT00015119094; ENSCCRP00015115437; ENSCCRG00015045633.
DR   Ensembl; ENSCCRT00020097175; ENSCCRP00020088885; ENSCCRG00020040796.
DR   GeneID; 109066813; -.
DR   KEGG; ccar:109066813; -.
DR   CTD; 798430; -.
DR   GeneTree; ENSGT00940000176232; -.
DR   OrthoDB; 1636375at2759; -.
DR   Proteomes; UP000694384; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0003785; F:actin monomer binding; IEA:InterPro.
DR   GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR   Gene3D; 1.20.5.520; -; 1.
DR   InterPro; IPR001152; Beta-thymosin.
DR   InterPro; IPR038386; Beta-thymosin_sf.
DR   PANTHER; PTHR12021; PTHR12021; 1.
DR   Pfam; PF01290; Thymosin; 1.
DR   PIRSF; PIRSF001828; Thymosin_beta; 1.
DR   SMART; SM00152; THY; 1.
DR   PROSITE; PS00500; THYMOSIN_B4; 1.
PE   3: Inferred from homology;
KW   Actin-binding; Cytoplasm; Cytoskeleton; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..46
FT                   /note="Thymosin beta-a"
FT                   /id="PRO_0000045935"
FT   REGION          21..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   46 AA;  5194 MW;  326B4129A478244C CRC64;
     MSDNPVKEEV QQFDKKCLKK TNTAEKNTLP TKEDIDQEKK AAEGGK