C71AN_ARATH
ID C71AN_ARATH Reviewed; 483 AA.
AC Q9STL0; Q304B2;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Cytochrome P450 71A23;
DE EC=1.14.-.-;
GN Name=CYP71A23; OrderedLocusNames=At3g48300; ORFNames=T29H11.180;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR EMBL; AL049659; CAB41168.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78397.1; -; Genomic_DNA.
DR PIR; T06712; T06712.
DR RefSeq; NP_680109.2; NM_148856.3.
DR AlphaFoldDB; Q9STL0; -.
DR SMR; Q9STL0; -.
DR STRING; 3702.AT3G48300.1; -.
DR PaxDb; Q9STL0; -.
DR PRIDE; Q9STL0; -.
DR ProteomicsDB; 240450; -.
DR EnsemblPlants; AT3G48300.1; AT3G48300.1; AT3G48300.
DR GeneID; 823988; -.
DR Gramene; AT3G48300.1; AT3G48300.1; AT3G48300.
DR KEGG; ath:AT3G48300; -.
DR Araport; AT3G48300; -.
DR TAIR; locus:504955634; AT3G48300.
DR eggNOG; KOG0156; Eukaryota.
DR HOGENOM; CLU_001570_4_1_1; -.
DR InParanoid; Q9STL0; -.
DR PhylomeDB; Q9STL0; -.
DR PRO; PR:Q9STL0; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9STL0; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR Gene3D; 1.10.630.10; -; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; SSF48264; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 2: Evidence at transcript level;
KW Heme; Iron; Membrane; Metal-binding; Monooxygenase; Oxidoreductase;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..483
FT /note="Cytochrome P450 71A23"
FT /id="PRO_0000052073"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT BINDING 429
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000250"
SQ SEQUENCE 483 AA; 54761 MW; 4CB55E1F4AC436C7 CRC64;
MILFLCLIIL FIITILFFKK HKTVNKIINF PSPPRLPLIG NLHQLSQHPH RSLCYLSHRY
GPLMLLHFGS VPVIVASTAE AARDVLKTHD RVFASRPRSK IFEKLLYKSR NMASAPYGEY
WRQMKSVSVL HLLSNKMVRS FQDVRQEEIT LMMETIRKSS SKPVNLSKIL SSLTNDVICR
VALGRKYGVG TDFKELIDRL MRQLGTFTIG SYVPWLAWTD WVSGLEARLE KTANDFDKLL
ERIVQDHEDG DGDKTDFVDV LLAAQRDKSF GFDIDRLSIK AIVLDAFVGG TDTSSTLVEW
EMTELLRHPT CLKKLQEEVR TICKGKSSVS EDDIQGMEYL KAVVKEALRL HPPVPLMVPH
QSTQDVRLRD NHIPAGTQVI VNLWAVGREA ATWGPDANEF RPERHLESPS DFRGQDFELI
PFGAGRRMCP GISFAVVLNE VVLANLVHGF DWQSIDDETD VAESIGSVIR RMHPLYVIPS
STT
