C71AQ_ARATH
ID C71AQ_ARATH Reviewed; 489 AA.
AC Q9STK7;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Cytochrome P450 71A26;
DE EC=1.14.-.-;
GN Name=CYP71A26; OrderedLocusNames=At3g48270; ORFNames=T29H11.210;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR EMBL; AL049659; CAB41171.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78393.1; -; Genomic_DNA.
DR PIR; T06715; T06715.
DR RefSeq; NP_680106.1; NM_148853.1.
DR AlphaFoldDB; Q9STK7; -.
DR SMR; Q9STK7; -.
DR STRING; 3702.AT3G48270.1; -.
DR PaxDb; Q9STK7; -.
DR PRIDE; Q9STK7; -.
DR ProteomicsDB; 240302; -.
DR EnsemblPlants; AT3G48270.1; AT3G48270.1; AT3G48270.
DR GeneID; 823985; -.
DR Gramene; AT3G48270.1; AT3G48270.1; AT3G48270.
DR KEGG; ath:AT3G48270; -.
DR Araport; AT3G48270; -.
DR TAIR; locus:504955639; AT3G48270.
DR eggNOG; KOG0156; Eukaryota.
DR HOGENOM; CLU_001570_4_1_1; -.
DR InParanoid; Q9STK7; -.
DR OMA; VPHSPIE; -.
DR OrthoDB; 702827at2759; -.
DR PhylomeDB; Q9STK7; -.
DR BioCyc; ARA:AT3G48270-MON; -.
DR PRO; PR:Q9STK7; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9STK7; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR Gene3D; 1.10.630.10; -; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; SSF48264; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme; Iron; Membrane; Metal-binding; Monooxygenase; Oxidoreductase;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..489
FT /note="Cytochrome P450 71A26"
FT /id="PRO_0000052076"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT BINDING 431
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000250"
SQ SEQUENCE 489 AA; 55833 MW; 224FC596FB3BAA75 CRC64;
MMIMFFLLCS IIFVVTIIIF RKQKRGKKRN TLPSPPGLPL IGNLHQLGRH PHRSLCSLSH
RYGPLMLLHF GRVPVLVVSS AELARDVLKT HDRVFASRPR SKIFEKLLYD KHDVASAPYG
EYWRQMKSVC VLHLFSNKMV RSFREVREEE ISLMMEKIRK SISLPVNLSK ILVSLTNDVI
CKVALGRKYG GETDFKELME RLNKLLGTFS VGSYVPWLAW IDWIRGLDCQ LEKTANDVDK
FFERVVQDHV DGNRDMTDFV DVLLAIQRDK TVGFEINRVS IKAIVMNVFV GGTDTSSTLM
EWAMTELLRH PKCLKRLQEE VRTICKDKSS VSEEEIQNMS YLKAVIKEAL RLHPPLPLMV
PHESTQDVRL GDHHIPAGTQ VLINAWAIGR EAATWGPDVE EFRPERHLDS SVDYRGQAFE
LIPFGSGRRI CPAISFAVVL NEVVLANLVH RFDWRLSVES TEDQTEVAES TGIAIHRMFP
LYAIASNTT
