ID   C71BH_ARATH             Reviewed;         502 AA.
AC   Q9LTM6;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 133.
DE   RecName: Full=Cytochrome P450 71B17;
DE            EC=1.14.-.-;
GN   Name=CYP71B17; OrderedLocusNames=At3g26160; ORFNames=MTC11.6;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT   features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:131-135(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR   EMBL; AB024038; BAB02436.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE77128.1; -; Genomic_DNA.
DR   RefSeq; NP_189247.1; NM_113523.1.
DR   AlphaFoldDB; Q9LTM6; -.
DR   SMR; Q9LTM6; -.
DR   STRING; 3702.AT3G26160.1; -.
DR   iPTMnet; Q9LTM6; -.
DR   PaxDb; Q9LTM6; -.
DR   PRIDE; Q9LTM6; -.
DR   EnsemblPlants; AT3G26160.1; AT3G26160.1; AT3G26160.
DR   GeneID; 822216; -.
DR   Gramene; AT3G26160.1; AT3G26160.1; AT3G26160.
DR   KEGG; ath:AT3G26160; -.
DR   Araport; AT3G26160; -.
DR   TAIR; locus:2093501; AT3G26160.
DR   eggNOG; KOG0156; Eukaryota.
DR   HOGENOM; CLU_001570_4_1_1; -.
DR   InParanoid; Q9LTM6; -.
DR   OMA; WISGQHK; -.
DR   OrthoDB; 702827at2759; -.
DR   PhylomeDB; Q9LTM6; -.
DR   BioCyc; ARA:AT3G26160-MON; -.
DR   PRO; PR:Q9LTM6; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LTM6; baseline and differential.
DR   Genevisible; Q9LTM6; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   Gene3D; 1.10.630.10; -; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; SSF48264; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme; Iron; Membrane; Metal-binding; Monooxygenase; Oxidoreductase;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..502
FT                   /note="Cytochrome P450 71B17"
FT                   /id="PRO_0000052095"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   BINDING         444
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   502 AA;  57204 MW;  20B1B9E3AA702DB9 CRC64;
     MAISLLCLFL ITFVSLTIVG CKIKRSIWNL PPSPPKLPVI GNLHQVGELP HRSFRRLAER
     TGHVMLLHLG FVPVTVISSR EAAEEVLRTH DLDCCSRPNL VGSRLISRGF KDLNFTPYGE
     EWKERRRFLV GELFCSKKLQ SFIYIKEVEC NFLVKKLSES AVDQSPVDLS KTLFWLAASI
     LFRVAFGQSF HESEFTDTDK IDELVFETET AQGSFTCSDF FPIAGLGWLV DWISGQHKRL
     NDVFLKLDAL LQHVIDDHSN PGRSKDHKDI VDVMLDVMHK QGKDDSLRLT IDHIKGLLTN
     IIIAGIDTGA LTMIWTMTEL ARNPEIMKKV QGEIRDRLGN NRERITKEDL DKVPFLNLVI
     KETFRLHPVA PLLLPRETMA HVKVQGYDIP PKRRILVNAW AIGRDPKLWT DPEEFKPERF
     IDSPVDYRGQ HFELLPFGSG RRICPGMAMG MATLELGLLN LLYFFDWKLP DGMSHKDIDT
     EEAGTLTVVK KVHLKLVPVR VP