ID   TYRT_STRGA              Reviewed;         134 AA.
AC   P55047;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Tyrosinase cofactor;
DE   AltName: Full=URF402;
DE   Flags: Precursor;
GN   Name=melC1;
OS   Streptomyces glaucescens.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DSM 40716 / ETH 22794 / Tue 49;
RX   PubMed=3118334; DOI=10.1093/nar/15.19.8106;
RA   Huber M., Huetter R., Lerch K.;
RT   "The promoter of the Streptomyces glaucescens mel operon.";
RL   Nucleic Acids Res. 15:8106-8106(1987).
CC   -!- FUNCTION: This protein may function to deliver copper to tyrosinase.
CC   -!- PTM: Predicted to be exported by the Tat system. The position of the
CC       signal peptide cleavage has not been experimentally proven.
CC   -!- SIMILARITY: Belongs to the melC1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Y00457; CAA68512.1; -; Genomic_DNA.
DR   PIR; A26986; A26986.
DR   RefSeq; WP_043498005.1; NZ_CP009438.1.
DR   AlphaFoldDB; P55047; -.
DR   SMR; P55047; -.
DR   STRING; 1907.SGLAU_02715; -.
DR   eggNOG; ENOG502ZNXC; Bacteria.
DR   OMA; YKGRRIQ; -.
DR   OrthoDB; 1953283at2; -.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1880.10; -; 1.
DR   InterPro; IPR023199; GriE/MELC1_sf.
DR   InterPro; IPR010928; MelC1.
DR   InterPro; IPR006311; TAT_signal.
DR   Pfam; PF06236; MelC1; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   3: Inferred from homology;
KW   Copper; Melanin biosynthesis; Signal.
FT   SIGNAL          1..32
FT                   /note="Tat-type signal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00648"
FT   CHAIN           33..134
FT                   /note="Tyrosinase cofactor"
FT                   /id="PRO_0000065707"
FT   REGION          27..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   134 AA;  13593 MW;  1E874145A7D1B9AE CRC64;
     MPELSRRRAL GAAAALAAAA GTQAVAAPAA TAAGHHPGPS TAATGHHPGT PASFDEVYKG
     RRIQGRPAAG GHHQHHGGGY AVLIDGVELH VMQNADGSWI SVVSHYDPVP TPRAAARAAV
     DELQGARLLP FPAN