ID   TYRT_STRGB              Reviewed;         126 AA.
AC   P55046;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Tyrosinase cofactor;
DE   Flags: Precursor;
GN   Name=melC1;
OS   Streptomyces galbus.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=33898;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 14077 / CBS 700.72 / DSM 40480 / NBRC 13399 / VKM Ac-160;
RA   Wehmeier U.F., Brass N., Roessler C., Piepersberg W.;
RT   "Cloning and characterization of the mel-operon from Streptomyces galbus
RT   DSM40480.";
RL   Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein may function to deliver copper to tyrosinase.
CC   -!- PTM: Predicted to be exported by the Tat system. The position of the
CC       signal peptide cleavage has not been experimentally proven.
CC   -!- SIMILARITY: Belongs to the melC1 family. {ECO:0000305}.
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DR   EMBL; X95705; CAA65004.1; -; Genomic_DNA.
DR   AlphaFoldDB; P55046; -.
DR   SMR; P55046; -.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1880.10; -; 1.
DR   InterPro; IPR023199; GriE/MELC1_sf.
DR   InterPro; IPR010928; MelC1.
DR   InterPro; IPR006311; TAT_signal.
DR   Pfam; PF06236; MelC1; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   3: Inferred from homology;
KW   Copper; Melanin biosynthesis; Signal.
FT   SIGNAL          1..33
FT                   /note="Tat-type signal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00648"
FT   CHAIN           34..126
FT                   /note="Tyrosinase cofactor"
FT                   /id="PRO_0000065705"
FT   REGION          21..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   126 AA;  12916 MW;  1785CC2C777C0106 CRC64;
     MPDITRRRAY TTAAAVAATA SAAAPTAAPA ATAAARHDHT APDSFDEVYK GRRIQGGPAS
     GGGHHHEHGG GYAVFVDGVQ LHVMQNADGT WISVVSHYAP VATPRAAARA AVDELQGAPL
     LPFPTN