ID   TYRT_STRLN              Reviewed;         140 AA.
AC   P55048;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Tyrosinase cofactor;
DE   Flags: Precursor;
GN   Name=melC1;
OS   Streptomyces lincolnensis.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=78-11;
RA   Zhang H.Z., Piepersberg W.;
RT   "Cloning and characterization of the mel-operon from S.lincolnensis 78-
RT   11.";
RL   Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein may function to deliver copper to tyrosinase.
CC   -!- PTM: Predicted to be exported by the Tat system. The position of the
CC       signal peptide cleavage has not been experimentally proven.
CC   -!- SIMILARITY: Belongs to the melC1 family. {ECO:0000305}.
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DR   EMBL; X95703; CAA64999.1; -; Genomic_DNA.
DR   AlphaFoldDB; P55048; -.
DR   SMR; P55048; -.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1880.10; -; 1.
DR   InterPro; IPR023199; GriE/MELC1_sf.
DR   InterPro; IPR010928; MelC1.
DR   InterPro; IPR006311; TAT_signal.
DR   Pfam; PF06236; MelC1; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   3: Inferred from homology;
KW   Copper; Melanin biosynthesis; Signal.
FT   SIGNAL          1..36
FT                   /note="Tat-type signal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00648"
FT   CHAIN           37..140
FT                   /note="Tyrosinase cofactor"
FT                   /id="PRO_0000065708"
SQ   SEQUENCE   140 AA;  14189 MW;  8752156617FD15A6 CRC64;
     MPRLTRRRAL TAAAALASGA GAGAGAQAAA APGAAAHDHG SPDVPLPCSL LDLLPLLPLL
     LDEVIKGRGI QGGPHRGGGH HHGTGYAVFL DGVELHVMRN ADGSWISVVS HYDPVPTPRA
     AARAAVDELQ GAKLVPFPAN