ID   C71BL_ARATH             Reviewed;         499 AA.
AC   Q9LTM2;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=Cytochrome P450 71B21;
DE            EC=1.14.-.-;
GN   Name=CYP71B21; OrderedLocusNames=At3g26190; ORFNames=MTC11.10;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT   features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:131-135(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR   EMBL; AB024038; BAB02440.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE77132.1; -; Genomic_DNA.
DR   RefSeq; NP_189250.1; NM_113526.1.
DR   AlphaFoldDB; Q9LTM2; -.
DR   SMR; Q9LTM2; -.
DR   BioGRID; 7551; 2.
DR   IntAct; Q9LTM2; 2.
DR   STRING; 3702.AT3G26190.1; -.
DR   PaxDb; Q9LTM2; -.
DR   PRIDE; Q9LTM2; -.
DR   ProteomicsDB; 240529; -.
DR   EnsemblPlants; AT3G26190.1; AT3G26190.1; AT3G26190.
DR   GeneID; 822220; -.
DR   Gramene; AT3G26190.1; AT3G26190.1; AT3G26190.
DR   KEGG; ath:AT3G26190; -.
DR   Araport; AT3G26190; -.
DR   TAIR; locus:2093541; AT3G26190.
DR   eggNOG; KOG0156; Eukaryota.
DR   HOGENOM; CLU_001570_4_1_1; -.
DR   InParanoid; Q9LTM2; -.
DR   OMA; QESIHAV; -.
DR   OrthoDB; 702827at2759; -.
DR   PhylomeDB; Q9LTM2; -.
DR   BioCyc; ARA:AT3G26190-MON; -.
DR   PRO; PR:Q9LTM2; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LTM2; baseline and differential.
DR   Genevisible; Q9LTM2; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   Gene3D; 1.10.630.10; -; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; SSF48264; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme; Iron; Membrane; Metal-binding; Monooxygenase; Oxidoreductase;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..499
FT                   /note="Cytochrome P450 71B21"
FT                   /id="PRO_0000052098"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   BINDING         441
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   499 AA;  56984 MW;  1C4641785A69A9A8 CRC64;
     MSIFLCFLLL LPLFLVFYKR LLPSKGKLPP GPISLPIIGN LHQLGKSLHR SFYKLSQEYG
     PVMFLRFGVV PVVVFSTKEA AEEVLKTHDL ETCTRPKLSA TGLFTYNFKD IGFAQYGEDW
     REMRKLAMLE LFSSKKLKAF RYIREEESEL LVKKVTESAQ TQTLVDLRKA LFSYTASIVC
     RLAFGQNFHE CDFVDMDKVE ELVLESETNL GSFAFIDFFP AGLGWAIDRI SGQHSRLHKA
     FARLSNFFQH VIDDHLKPWQ SEDHSDIVGV MLDMINKESK VGSFKVTYDH LKGVMSDVFL
     AGVNAGAITM IWALTELTRH PRVMKKLQQE IRELLGDNKE KITEQDLEKV HYLKLVIQET
     FRLHPPAPLL LPRETMSDVK IQGYNIPKNT MIEINTYAIG RDPNCWTNPN EFIPERFVDS
     PIDYKGQHFE LLPFGGGRRI CPGMATGMTI VELGLLNVLY FFDWSLPYGM AIADINMEEA
     GAFVIAKKVP LELVPVLHY