C71BS_ARATH
ID C71BS_ARATH Reviewed; 490 AA.
AC Q9SAE3;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Cytochrome P450 71B28;
DE EC=1.14.-.-;
GN Name=CYP71B28; OrderedLocusNames=At1g13090; ORFNames=F3F19.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR EMBL; AC007357; AAD31062.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM58391.1; -; Genomic_DNA.
DR EMBL; AF325097; AAK17165.1; -; mRNA.
DR EMBL; AY062833; AAL32911.1; -; mRNA.
DR EMBL; AY128747; AAM91147.1; -; mRNA.
DR PIR; A86265; A86265.
DR RefSeq; NP_172768.1; NM_101179.3.
DR AlphaFoldDB; Q9SAE3; -.
DR SMR; Q9SAE3; -.
DR STRING; 3702.AT1G13090.1; -.
DR PaxDb; Q9SAE3; -.
DR PRIDE; Q9SAE3; -.
DR ProteomicsDB; 240268; -.
DR EnsemblPlants; AT1G13090.2; AT1G13090.2; AT1G13090.
DR GeneID; 837866; -.
DR Gramene; AT1G13090.2; AT1G13090.2; AT1G13090.
DR KEGG; ath:AT1G13090; -.
DR Araport; AT1G13090; -.
DR TAIR; locus:2031915; AT1G13090.
DR eggNOG; KOG0156; Eukaryota.
DR HOGENOM; CLU_001570_4_1_1; -.
DR InParanoid; Q9SAE3; -.
DR OMA; VERQHDS; -.
DR OrthoDB; 702827at2759; -.
DR PhylomeDB; Q9SAE3; -.
DR PRO; PR:Q9SAE3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SAE3; baseline and differential.
DR Genevisible; Q9SAE3; AT.
DR GO; GO:0005576; C:extracellular region; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR Gene3D; 1.10.630.10; -; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; SSF48264; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 2: Evidence at transcript level;
KW Heme; Iron; Membrane; Metal-binding; Monooxygenase; Oxidoreductase;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..490
FT /note="Cytochrome P450 71B28"
FT /id="PRO_0000052105"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT BINDING 440
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000250"
SQ SEQUENCE 490 AA; 56537 MW; 37FD31DDA6491C67 CRC64;
MSVFLCFLCL LPLILIFLKN LKPSKWKLPP GPKKLPIIGN LHQRRELHPR NSRNLSEKYG
PIVFLRYGFV PVVVISSKEA AEEVLKTHDL ECCSRPETVG TRAISYNFKD IGFAPYGEDW
RTMRKLSVVE LFSSKKLQSF RYIREEENDL CVKKLSDLAS RRSLVNLEKT LFTLVGSIVC
RIGFGINLRE CEFVDEDSID DLVHKSEDVI RNSIFSDFFP GLMGRLIEWI FSERKRLNRL
YSEVDTFFQN ILDDHLKPGR ESSDIIDVMI DMMKKQEKEG DSFKFTTDHL KGMISDIFLA
GVGTSSTTLI WAMTELIRNP RVMKKVQDEI RTTLGDKKER ITEEDLNQLH YFKLMVKEIF
RLHPAAPLLL PRETLSHVKI QGYDIPAKTQ IMINAYAIAR DPKLWTNPDE FNPDRFLDSS
IDYRGLNFEL LPFGSGRRIC PGMTMGIAIV ELGLLNLLYF FDWGLPEKEE AKEIITGNEV
ALDLVQVFLH
