ID   C71BW_ARATH             Reviewed;         500 AA.
AC   Q9LIP5; Q53XE2;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=Cytochrome P450 71B35;
DE            EC=1.14.-.-;
GN   Name=CYP71B35; OrderedLocusNames=At3g26310; ORFNames=F20C19.3;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA   Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT   features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT   clones.";
RL   DNA Res. 7:217-221(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Cheuk R.F., Chen H., Kim C.J., Shinn P., Carninci P., Hayashizaki Y.,
RA   Ishida J., Kamiya A., Kawai J., Narusaka M., Sakurai T., Satou M., Seki M.,
RA   Shinozaki K., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR   EMBL; AP001298; BAB02191.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE77144.1; -; Genomic_DNA.
DR   EMBL; BT011754; AAS49117.1; -; mRNA.
DR   RefSeq; NP_189262.1; NM_113538.2.
DR   AlphaFoldDB; Q9LIP5; -.
DR   SMR; Q9LIP5; -.
DR   BioGRID; 7566; 1.
DR   STRING; 3702.AT3G26310.1; -.
DR   iPTMnet; Q9LIP5; -.
DR   PaxDb; Q9LIP5; -.
DR   PRIDE; Q9LIP5; -.
DR   ProteomicsDB; 240453; -.
DR   EnsemblPlants; AT3G26310.1; AT3G26310.1; AT3G26310.
DR   GeneID; 822235; -.
DR   Gramene; AT3G26310.1; AT3G26310.1; AT3G26310.
DR   KEGG; ath:AT3G26310; -.
DR   Araport; AT3G26310; -.
DR   TAIR; locus:2079306; AT3G26310.
DR   eggNOG; KOG0156; Eukaryota.
DR   HOGENOM; CLU_001570_4_1_1; -.
DR   InParanoid; Q9LIP5; -.
DR   OMA; INEWANE; -.
DR   OrthoDB; 702827at2759; -.
DR   PhylomeDB; Q9LIP5; -.
DR   BioCyc; ARA:AT3G26310-MON; -.
DR   PRO; PR:Q9LIP5; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LIP5; baseline and differential.
DR   Genevisible; Q9LIP5; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IBA:GO_Central.
DR   Gene3D; 1.10.630.10; -; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; SSF48264; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   2: Evidence at transcript level;
KW   Heme; Iron; Membrane; Metal-binding; Monooxygenase; Oxidoreductase;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..500
FT                   /note="Cytochrome P450 71B35"
FT                   /id="PRO_0000052109"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   BINDING         439
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   500 AA;  57322 MW;  5596740000F4C379 CRC64;
     MAHIWLLPLI FLVCILLAVF NHKKHPKYRQ FPCPPGFPII GNLHQIGELP HQTLWKLSKK
     YGPVMHLMLG RVPTVVVSSS DTARQVLRVH DLHCCTRPSL SGPRELSYNY LDIAFSPYDD
     YWKEVRKLCV QELFSTKQVH SIQPIKDEEV KKMIDSIAES ASQKNPVNLN NKCLELTVSV
     VCRTAFGVSF EGTVLNSDRF NKIVREALEM LGSFSAADFI PYVGWIIDVL TGLQGRRERS
     KRDLNAFFEQ MFDLHKEGKK EGNEDFVDLL LRLEKEEAVL GNDKLTRNHI KAILLDVLLA
     GIDTSAITMT WAMTELARNP RVMKKVQSEI RTQMGNRSMI SFEDMDQLEY LKMVIKETWR
     LHPTTPLLLP REAMSEFDIN GYTIPVKTRL HVNVWAIGRD PDTWKDPEVF LPERFMDNNI
     DAKGQHFELL PFGGGRRICP AIYMGTTMVE FGLANLLYHF DWKLPEGVEV KDIDVEEAPG
     LTVNKKNELL LVPEMRRSCG