ID   C71BY_ARATH             Reviewed;         500 AA.
AC   Q9LIP3;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2002, sequence version 2.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=Cytochrome P450 71B37;
DE            EC=1.14.-.-;
GN   Name=CYP71B37; OrderedLocusNames=At3g26330; ORFNames=F20C19.5;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA   Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT   features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT   clones.";
RL   DNA Res. 7:217-221(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   CONCEPTUAL TRANSLATION.
RA   Bak S., Paquette S.;
RL   Unpublished observations (APR-2001).
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB02193.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AP001298; BAB02193.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002686; AEE77146.1; -; Genomic_DNA.
DR   RefSeq; NP_189264.3; NM_113540.5.
DR   AlphaFoldDB; Q9LIP3; -.
DR   SMR; Q9LIP3; -.
DR   STRING; 3702.AT3G26330.1; -.
DR   PaxDb; Q9LIP3; -.
DR   PRIDE; Q9LIP3; -.
DR   ProteomicsDB; 240567; -.
DR   EnsemblPlants; AT3G26330.1; AT3G26330.1; AT3G26330.
DR   GeneID; 822237; -.
DR   Gramene; AT3G26330.1; AT3G26330.1; AT3G26330.
DR   KEGG; ath:AT3G26330; -.
DR   Araport; AT3G26330; -.
DR   TAIR; locus:2079316; AT3G26330.
DR   eggNOG; KOG0156; Eukaryota.
DR   HOGENOM; CLU_001570_4_1_1; -.
DR   InParanoid; Q9LIP3; -.
DR   OMA; FNDYWKE; -.
DR   OrthoDB; 702827at2759; -.
DR   PhylomeDB; Q9LIP3; -.
DR   BioCyc; ARA:AT3G26330-MON; -.
DR   PRO; PR:Q9LIP3; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LIP3; baseline and differential.
DR   Genevisible; Q9LIP3; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IBA:GO_Central.
DR   Gene3D; 1.10.630.10; -; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; SSF48264; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme; Iron; Membrane; Metal-binding; Monooxygenase; Oxidoreductase;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..500
FT                   /note="Cytochrome P450 71B37"
FT                   /id="PRO_0000052111"
FT   TRANSMEM        2..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   BINDING         440
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   500 AA;  56843 MW;  B36088363D918FE1 CRC64;
     MATIWFLPLL FLSCLLLAAL RLKKRRQHQR KPPSPPGFPI IGNLHQLGEL PHQSLWSLSK
     KYGPVMLLKF GSIPTVVVSS SETAKQALKI HDLNCCSRPS LAGPRALSYN YLDIVFSPFN
     DYWKELRRMC VQELFSPKQV HLIQPIREEE VKKLMNSFSE SAAQKTPVNL SEKLASLTVG
     VICKAAFGVS FQGTVLNSDN FDKLIHDAFL FLGSFSASDY FPNVGWIIDW LTGLQGQRER
     SVRGLDAFYE QMFDLHKQGN KEGVEDFVDL LLKLEKEETV LGYGKLTRNH IKAVLMNVLL
     GGIGTSAITM TWAMTELMRN PRVMKKVQSE IRNQIGGKSM ICLDDIDQLH YLKMVINETW
     RLHPPAPLLV PREVMSEFEI NGYTIPAKTR LYVNVWGIGR DPDTWKDPEE FLPERFVNSN
     IDAKGQNFEL LPFGSGRRMC PAMYMGTTMV EFGLANLLYH FDWKLPEGMV VEDIDMEESP
     GLNASKKNEL VLVPRKYLNL