U17_HHV6U
ID U17_HHV6U Reviewed; 133 AA.
AC Q69552; Q69039;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 02-JUN-2021, entry version 55.
DE RecName: Full=Protein U17;
GN Name=U17/U16;
OS Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human B
OS lymphotropic virus).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX NCBI_TaxID=10370;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND ALTERNATIVE SPLICING (ISOFORMS 1 AND
RP 3).
RX PubMed=8289364; DOI=10.1128/jvi.68.2.597-610.1994;
RA Nicholas J., Martin M.E.D.;
RT "Nucleotide sequence analysis of a 38.5-kilobase-pair region of the genome
RT of human herpesvirus 6 encoding human cytomegalovirus immediate-early gene
RT homologs and transactivating functions.";
RL J. Virol. 68:597-610(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=7747482; DOI=10.1006/viro.1995.1228;
RA Gompels U.A., Nicholas J., Lawrence G.L., Jones M., Thomson B.J.,
RA Martin M.E.D., Efstathiou S., Craxton M.A., Macaulay H.A.;
RT "The DNA sequence of human herpesvirus-6: structure, coding content, and
RT genome evolution.";
RL Virology 209:29-51(1995).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=2; Synonyms=Protein U17, EFLF1;
CC IsoId=Q69552-1; Sequence=Displayed;
CC Name=1; Synonyms=Protein U17/U16, Protein U16exon1-2;
CC IsoId=Q69551-1; Sequence=External;
CC Name=3; Synonyms=Protein U16, EFLF2;
CC IsoId=Q69551-2; Sequence=External;
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA16722.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; L25528; AAA16722.1; ALT_INIT; Genomic_DNA.
DR EMBL; X83413; CAA58397.1; -; Genomic_DNA.
DR PIR; T09309; T09309.
DR RefSeq; NP_042910.2; NC_001664.2.
DR PRIDE; Q69552; -.
DR DNASU; 1487923; -.
DR GeneID; 1487923; -.
DR KEGG; vg:1487923; -.
DR Proteomes; UP000009295; Genome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 4: Predicted;
KW Alternative splicing; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..133
FT /note="Protein U17"
FT /id="PRO_0000343648"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 133 AA; 15538 MW; 441A1292EB7E7CA1 CRC64;
MADERTSDSV KTRYDIALMK LNDIKIAVFR DSLSTYVEQK TGLTIQFNWP KSRCLVISTL
CKIPFPTKSA AELQEMCKYQ CFVSVLWCVI LVFVVKIKLF FLLNKVRYYF AARKDCNYLD
MFLSGERRLV MCA