U1SBP_DANRE
ID U1SBP_DANRE Reviewed; 208 AA.
AC Q4KMD3;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 02-AUG-2005, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=U11/U12 small nuclear ribonucleoprotein 35 kDa protein;
DE Short=U11/U12 snRNP 35 kDa protein;
DE AltName: Full=U1 snRNP-binding protein homolog;
GN Name=snrnp35; Synonyms=u1snrnpbp; ORFNames=zgc:112337;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Eye;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR EMBL; BC098619; AAH98619.1; -; mRNA.
DR RefSeq; NP_001025412.1; NM_001030241.1.
DR AlphaFoldDB; Q4KMD3; -.
DR SMR; Q4KMD3; -.
DR STRING; 7955.ENSDARP00000065242; -.
DR PaxDb; Q4KMD3; -.
DR PRIDE; Q4KMD3; -.
DR Ensembl; ENSDART00000172191; ENSDARP00000135151; ENSDARG00000099913.
DR GeneID; 569999; -.
DR KEGG; dre:569999; -.
DR CTD; 11066; -.
DR ZFIN; ZDB-GENE-050706-77; snrnp35.
DR eggNOG; KOG0113; Eukaryota.
DR GeneTree; ENSGT00940000157648; -.
DR HOGENOM; CLU_035088_1_0_1; -.
DR InParanoid; Q4KMD3; -.
DR OMA; FEHERDF; -.
DR OrthoDB; 1430110at2759; -.
DR PhylomeDB; Q4KMD3; -.
DR TreeFam; TF331614; -.
DR Reactome; R-DRE-72165; mRNA Splicing - Minor Pathway.
DR PRO; PR:Q4KMD3; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 10.
DR Bgee; ENSDARG00000099913; Expressed in mature ovarian follicle and 24 other tissues.
DR GO; GO:0005689; C:U12-type spliceosomal complex; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0017069; F:snRNA binding; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR CDD; cd12237; RRM_snRNP35; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034146; snRNP35_RRM.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
DR PROSITE; PS50102; RRM; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; RNA-binding.
FT CHAIN 1..208
FT /note="U11/U12 small nuclear ribonucleoprotein 35 kDa
FT protein"
FT /id="PRO_0000307910"
FT DOMAIN 50..128
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 133..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..208
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 208 AA; 24588 MW; D49AB42D28258AC9 CRC64;
MEWSPVAKVY DPLKAGSIDG TDVEPHDAGV WRAMLARYKP NRGVCGDPDL TLFVARLNPQ
TTEEKLRDVF SKFGDIRRLR LVRDVVTGFS KRYAFIEYKE ERSLKRAWRD ANKLILDQYE
LLVDVEQERT LPGWRPRRLG GGQGGQKESG QLRFGGRDRP FRKPINLSTR RPAEPRGRET
ERERDRRDYR DRRHERTHTE DRTHRHTY