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U1SBP_DANRE
ID   U1SBP_DANRE             Reviewed;         208 AA.
AC   Q4KMD3;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=U11/U12 small nuclear ribonucleoprotein 35 kDa protein;
DE            Short=U11/U12 snRNP 35 kDa protein;
DE   AltName: Full=U1 snRNP-binding protein homolog;
GN   Name=snrnp35; Synonyms=u1snrnpbp; ORFNames=zgc:112337;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC098619; AAH98619.1; -; mRNA.
DR   RefSeq; NP_001025412.1; NM_001030241.1.
DR   AlphaFoldDB; Q4KMD3; -.
DR   SMR; Q4KMD3; -.
DR   STRING; 7955.ENSDARP00000065242; -.
DR   PaxDb; Q4KMD3; -.
DR   PRIDE; Q4KMD3; -.
DR   Ensembl; ENSDART00000172191; ENSDARP00000135151; ENSDARG00000099913.
DR   GeneID; 569999; -.
DR   KEGG; dre:569999; -.
DR   CTD; 11066; -.
DR   ZFIN; ZDB-GENE-050706-77; snrnp35.
DR   eggNOG; KOG0113; Eukaryota.
DR   GeneTree; ENSGT00940000157648; -.
DR   HOGENOM; CLU_035088_1_0_1; -.
DR   InParanoid; Q4KMD3; -.
DR   OMA; FEHERDF; -.
DR   OrthoDB; 1430110at2759; -.
DR   PhylomeDB; Q4KMD3; -.
DR   TreeFam; TF331614; -.
DR   Reactome; R-DRE-72165; mRNA Splicing - Minor Pathway.
DR   PRO; PR:Q4KMD3; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 10.
DR   Bgee; ENSDARG00000099913; Expressed in mature ovarian follicle and 24 other tissues.
DR   GO; GO:0005689; C:U12-type spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0017069; F:snRNA binding; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   CDD; cd12237; RRM_snRNP35; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR034146; snRNP35_RRM.
DR   Pfam; PF00076; RRM_1; 1.
DR   SMART; SM00360; RRM; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS50102; RRM; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..208
FT                   /note="U11/U12 small nuclear ribonucleoprotein 35 kDa
FT                   protein"
FT                   /id="PRO_0000307910"
FT   DOMAIN          50..128
FT                   /note="RRM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          133..208
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        172..208
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   208 AA;  24588 MW;  D49AB42D28258AC9 CRC64;
     MEWSPVAKVY DPLKAGSIDG TDVEPHDAGV WRAMLARYKP NRGVCGDPDL TLFVARLNPQ
     TTEEKLRDVF SKFGDIRRLR LVRDVVTGFS KRYAFIEYKE ERSLKRAWRD ANKLILDQYE
     LLVDVEQERT LPGWRPRRLG GGQGGQKESG QLRFGGRDRP FRKPINLSTR RPAEPRGRET
     ERERDRRDYR DRRHERTHTE DRTHRHTY
 
 
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