ID   U1SBP_RAT               Reviewed;         244 AA.
AC   Q5U1W5;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=U11/U12 small nuclear ribonucleoprotein 35 kDa protein;
DE            Short=U11/U12 snRNP 35 kDa protein;
DE   AltName: Full=U1 snRNP-binding protein homolog;
GN   Name=Snrnp35; Synonyms=U1snrnpbp;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBUNIT: Component of the U11/U12 snRNPs that are part of the U12-type
CC       spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC086435; AAH86435.1; -; mRNA.
DR   RefSeq; NP_001014149.1; NM_001014127.1.
DR   AlphaFoldDB; Q5U1W5; -.
DR   SMR; Q5U1W5; -.
DR   STRING; 10116.ENSRNOP00000001402; -.
DR   PaxDb; Q5U1W5; -.
DR   GeneID; 360803; -.
DR   KEGG; rno:360803; -.
DR   UCSC; RGD:1310724; rat.
DR   CTD; 11066; -.
DR   RGD; 1310724; Snrnp35.
DR   eggNOG; KOG0113; Eukaryota.
DR   InParanoid; Q5U1W5; -.
DR   PhylomeDB; Q5U1W5; -.
DR   Reactome; R-RNO-72165; mRNA Splicing - Minor Pathway.
DR   PRO; PR:Q5U1W5; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0005634; C:nucleus; ISO:RGD.
DR   GO; GO:0005689; C:U12-type spliceosomal complex; ISO:RGD.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0017069; F:snRNA binding; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   CDD; cd12237; RRM_snRNP35; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR034146; snRNP35_RRM.
DR   Pfam; PF00076; RRM_1; 1.
DR   SMART; SM00360; RRM; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS50102; RRM; 1.
PE   2: Evidence at transcript level;
KW   Isopeptide bond; mRNA processing; mRNA splicing; Nucleus;
KW   Reference proteome; RNA-binding; Spliceosome; Ubl conjugation.
FT   CHAIN           1..244
FT                   /note="U11/U12 small nuclear ribonucleoprotein 35 kDa
FT                   protein"
FT                   /id="PRO_0000307909"
FT   DOMAIN          51..129
FT                   /note="RRM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          146..244
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        170..244
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CROSSLNK        172
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q16560"
SQ   SEQUENCE   244 AA;  29204 MW;  07B008D0AF05575B CRC64;
     MSDWMPIAKE YDPLKAGSID GTDEDPHDRA VWRAMLARYV PNKGVTGDPL LTLFVARLNS
     QTKEEKLKEV FSRYGDIRRL RLVRDLVTGF SKGYAFIEYK EERALLKAYR DADGLVIDQH
     EIFVDYELER TLRGWIPRRL GGGLGGKKES GQLRFGGRDR PFRKPINLPV VKNEPHREGK
     RERRERSRSR DRHWDPRPRE RDHDRGREKH WQDRARVWPE NDWEREREFR DERAKTRDKR
     DRSK