U239_DROME
ID U239_DROME Reviewed; 87 AA.
AC O77286; Q4V3Y1;
DT 30-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Protein anon-73B1;
GN Name=anon-73B1; Synonyms=anon73B1; ORFNames=CG4101;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=PE, PR, and VE;
RX PubMed=11361347; DOI=10.1007/s004380000423;
RA Bichon A., Boukhatem N., Gay P., Dru P., Terzian H., Petitjean A.-M.,
RA Lemeunier F., Contamine D.;
RT "Genetic and molecular features of Su(P), a gene that interacts with
RT ref(2)P in male fertility of Drosophila melanogaster.";
RL Mol. Genet. Genomics 265:354-361(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Berkeley;
RA Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A., Pacleb J.M.,
RA Park S., Wan K.H., Yu C., Celniker S.E.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the UPF0239 family. {ECO:0000305}.
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DR EMBL; AJ250305; CAB58344.1; -; Genomic_DNA.
DR EMBL; AJ250306; CAB58346.1; -; Genomic_DNA.
DR EMBL; AJ250307; CAB58348.1; -; Genomic_DNA.
DR EMBL; AJ011320; CAA09594.1; -; Genomic_DNA.
DR EMBL; AE014296; AAF49433.1; -; Genomic_DNA.
DR EMBL; BT023225; AAY55641.1; -; mRNA.
DR RefSeq; NP_648908.1; NM_140651.3.
DR AlphaFoldDB; O77286; -.
DR SMR; O77286; -.
DR IntAct; O77286; 3.
DR STRING; 7227.FBpp0075074; -.
DR PaxDb; O77286; -.
DR DNASU; 39857; -.
DR EnsemblMetazoa; FBtr0075314; FBpp0075074; FBgn0025558.
DR GeneID; 39857; -.
DR KEGG; dme:Dmel_CG4101; -.
DR UCSC; CG4101-RA; d. melanogaster.
DR FlyBase; FBgn0025558; CG4101.
DR VEuPathDB; VectorBase:FBgn0025558; -.
DR eggNOG; ENOG502S6QI; Eukaryota.
DR GeneTree; ENSGT00390000003422; -.
DR HOGENOM; CLU_189363_0_0_1; -.
DR InParanoid; O77286; -.
DR OMA; PYHRSRK; -.
DR OrthoDB; 1597344at2759; -.
DR PhylomeDB; O77286; -.
DR BioGRID-ORCS; 39857; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 39857; -.
DR PRO; PR:O77286; -.
DR Proteomes; UP000000803; Chromosome 3L.
DR Bgee; FBgn0025558; Expressed in saliva-secreting gland and 26 other tissues.
DR ExpressionAtlas; O77286; baseline and differential.
DR Genevisible; O77286; DM.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR009621; UPF0239.
DR PANTHER; PTHR14409; PTHR14409; 1.
DR Pfam; PF06783; UPF0239; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..87
FT /note="Protein anon-73B1"
FT /id="PRO_0000194182"
FT TRANSMEM 25..47
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 51..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..76
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 87 AA; 9630 MW; 51EF54E4BEAADE78 CRC64;
MSASADSLGA AAALDKYGDE DIFSLLIRYG LYVGALFQFV CISAAVLMEN NPDGQSNPES
GEVTEREGEP VRTRLHKIRK LEKKKRR