ID   U23_HHV6U               Reviewed;         236 AA.
AC   Q69558; Q69047;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 60.
DE   RecName: Full=Glycoprotein U23;
DE   Flags: Precursor;
GN   Name=U23; Synonyms=EqLF1;
OS   Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human B
OS   lymphotropic virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX   NCBI_TaxID=10370;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8289364; DOI=10.1128/jvi.68.2.597-610.1994;
RA   Nicholas J., Martin M.E.D.;
RT   "Nucleotide sequence analysis of a 38.5-kilobase-pair region of the genome
RT   of human herpesvirus 6 encoding human cytomegalovirus immediate-early gene
RT   homologs and transactivating functions.";
RL   J. Virol. 68:597-610(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=7747482; DOI=10.1006/viro.1995.1228;
RA   Gompels U.A., Nicholas J., Lawrence G.L., Jones M., Thomson B.J.,
RA   Martin M.E.D., Efstathiou S., Craxton M.A., Macaulay H.A.;
RT   "The DNA sequence of human herpesvirus-6: structure, coding content, and
RT   genome evolution.";
RL   Virology 209:29-51(1995).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA16730.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; L25528; AAA16730.1; ALT_INIT; Genomic_DNA.
DR   EMBL; X83413; CAA58403.1; -; Genomic_DNA.
DR   PIR; T09317; T09317.
DR   RefSeq; NP_042916.1; NC_001664.2.
DR   SMR; Q69558; -.
DR   PRIDE; Q69558; -.
DR   DNASU; 1487989; -.
DR   GeneID; 1487989; -.
DR   KEGG; vg:1487989; -.
DR   Proteomes; UP000009295; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..236
FT                   /note="Glycoprotein U23"
FT                   /id="PRO_0000342578"
FT   TRANSMEM        184..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        67
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        80
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        103
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   236 AA;  26523 MW;  C4CF8711102EEDC4 CRC64;
     MLFLSFLLVC LCEEVRMLNL MTTEVSATEF ASIASKNMET DVSTSSDYLT GKSETTFSAN
     SETWGKNVTE ISIDSETYLN QSFMVTSTLA VETTDRSIGN NVNVTSSFPT VKGDETQNIE
     TSFTVISAST FSDVSEKTPQ GLSTKSTPKK TVQALWETDT VQVLEFTDTH EGDEEYFKDF
     LSSLVIWIGG ISFIGAFVIL IVILCNWYKK DKQRSLFWDE EKKPDVQMRR DVKTCR