U2D2L_HUMAN
ID U2D2L_HUMAN Reviewed; 75 AA.
AC Q8IWF7;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Putative ubiquitin-conjugating enzyme E2 D2-like protein;
DE AltName: Full=Ubiquitin carrier protein D2-like;
DE AltName: Full=Ubiquitin-conjugating enzyme E2D N-terminal-like;
DE AltName: Full=Ubiquitin-protein ligase D2-like;
GN Name=UBE2DNL; Synonyms=UBE2D2L;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family.
CC {ECO:0000255|PROSITE-ProRule:PRU00388}.
CC -!- CAUTION: Could be the product of a pseudogene. Probably inactive as a
CC ubiquitin-conjugating enzyme since it lacks the essential active site
CC cysteine. {ECO:0000305}.
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DR EMBL; BC040290; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q8IWF7; -.
DR SMR; Q8IWF7; -.
DR IntAct; Q8IWF7; 11.
DR BioMuta; HGNC:28656; -.
DR PRIDE; Q8IWF7; -.
DR GeneCards; UBE2DNL; -.
DR HGNC; HGNC:28656; UBE2DNL.
DR neXtProt; NX_Q8IWF7; -.
DR InParanoid; Q8IWF7; -.
DR PhylomeDB; Q8IWF7; -.
DR PathwayCommons; Q8IWF7; -.
DR SignaLink; Q8IWF7; -.
DR Pharos; Q8IWF7; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q8IWF7; protein.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0061631; F:ubiquitin conjugating enzyme activity; IBA:GO_Central.
DR GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IBA:GO_Central.
DR GO; GO:0000209; P:protein polyubiquitination; IBA:GO_Central.
DR GO; GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IBA:GO_Central.
DR Gene3D; 3.10.110.10; -; 1.
DR InterPro; IPR000608; UBQ-conjugat_E2.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR Pfam; PF00179; UQ_con; 1.
DR SUPFAM; SSF54495; SSF54495; 1.
DR PROSITE; PS50127; UBC_2; 1.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..75
FT /note="Putative ubiquitin-conjugating enzyme E2 D2-like
FT protein"
FT /id="PRO_0000254089"
FT DOMAIN 1..75
FT /note="UBC core"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00388"
SQ SEQUENCE 75 AA; 8761 MW; 97FF955C48458183 CRC64;
MALKLIHKEF LELARDPQPH CSAGPVWDDM LHWQATITRP NDSSYLGGVF FLKFPSDYLF
KPPKIKFTNG IYHQR