U2Q2L_HUMAN
ID U2Q2L_HUMAN Reviewed; 131 AA.
AC H0YL09;
DT 14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT 22-FEB-2012, sequence version 1.
DT 03-AUG-2022, entry version 54.
DE RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;
GN Name=UBE2Q2L;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16572171; DOI=10.1038/nature04601;
RA Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B.,
RA Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S.,
RA Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT "Analysis of the DNA sequence and duplication history of human chromosome
RT 15.";
RL Nature 440:671-675(2006).
CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family.
CC {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. Probably inactive as a
CC ubiquitin-conjugating enzyme since it lacks the essential active site
CC cysteine. Derived from EST data. {ECO:0000305}.
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DR EMBL; AC136698; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001230460.1; NM_001243531.1.
DR AlphaFoldDB; H0YL09; -.
DR STRING; 9606.ENSP00000453012; -.
DR iPTMnet; H0YL09; -.
DR PhosphoSitePlus; H0YL09; -.
DR BioMuta; UBE2Q2L; -.
DR MassIVE; H0YL09; -.
DR PaxDb; H0YL09; -.
DR PRIDE; H0YL09; -.
DR DNASU; 100505679; -.
DR GeneID; 100505679; -.
DR UCSC; uc021stj.2; human.
DR CTD; 100505679; -.
DR DisGeNET; 100505679; -.
DR GeneCards; UBE2Q2L; -.
DR HGNC; HGNC:44656; UBE2Q2L.
DR neXtProt; NX_H0YL09; -.
DR eggNOG; ENOG502TG6H; Eukaryota.
DR HOGENOM; CLU_158730_0_0_1; -.
DR InParanoid; H0YL09; -.
DR OrthoDB; 1492890at2759; -.
DR PhylomeDB; H0YL09; -.
DR BioGRID-ORCS; 100505679; 32 hits in 633 CRISPR screens.
DR ChiTaRS; UBE2Q2L; human.
DR GenomeRNAi; 100505679; -.
DR Pharos; H0YL09; Tdark.
DR Proteomes; UP000005640; Chromosome 15.
DR RNAct; H0YL09; protein.
DR Genevisible; H0YL09; HS.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..131
FT /note="Putative ubiquitin-conjugating enzyme E2Q2-like
FT protein"
FT /id="PRO_0000429012"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 131 AA; 14853 MW; 2AEB65923CE44A75 CRC64;
MGPAVLGQGQ EGQPEARACS GLLQPPKRPI VFKEKLTMKT DSLMEEKLEC SLWCCLSDPS
IPGRCCVLER RIVPWMQQES YSSSSPIWSV DSDEPNLTSV LERLEDTKEN SSVRKETKLF
SLFLMNIIFR N