ID   U2_BPMU                 Reviewed;         177 AA.
AC   P0DJY5;
DT   14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT   14-MAY-2014, sequence version 1.
DT   23-FEB-2022, entry version 23.
DE   RecName: Full=Tail fiber assembly protein U';
DE   AltName: Full=Gene product U';
DE            Short=gpU';
GN   Name=U'; OrderedLocusNames=Mup51;
OS   Escherichia phage Mu (Bacteriophage Mu).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Muvirus.
OX   NCBI_TaxID=10677;
OH   NCBI_TaxID=543; Enterobacteriaceae.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11922669; DOI=10.1006/jmbi.2002.5437;
RA   Morgan G.J., Hatfull G.F., Casjens S., Hendrix R.W.;
RT   "Bacteriophage Mu genome sequence: analysis and comparison with Mu-like
RT   prophages in Haemophilus, Neisseria and Deinococcus.";
RL   J. Mol. Biol. 317:337-359(2002).
RN   [2]
RP   INDUCTION.
RX   PubMed=8293968; DOI=10.1093/genetics/135.3.619;
RA   Chiang L.W., Howe M.M.;
RT   "Mutational analysis of a C-dependent late promoter of bacteriophage Mu.";
RL   Genetics 135:619-629(1993).
RN   [3]
RP   SUBCELLULAR LOCATION.
RX   PubMed=8599204; DOI=10.1006/viro.1996.0107;
RA   Grimaud R.;
RT   "Bacteriophage Mu head assembly.";
RL   Virology 217:200-210(1996).
CC   -!- FUNCTION: Chaperone involved in tail fiber assembly. Remains associated
CC       to the tail fiber and participates in the host receptor binding. Binds
CC       to the primary receptor (Probable). Two alternate tail fiber assembly
CC       proteins U and U' are encoded extending the host range of the virus.
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:8599204}. Host
CC       cytoplasm {ECO:0000305|PubMed:8599204}. Note=Tail fiber. {ECO:0000305}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       Expression of late genes is activated by the viral late transcription
CC       activator C. Expressed alternatively with tail fiber assembly protein
CC       U. The switch from S-U to S'-U' is performed through inversion of a DNA
CC       segment called G by the phage invertase protein Gin.
CC       {ECO:0000269|PubMed:8293968}.
CC   -!- MISCELLANEOUS: The orientation of the G segment is defined as G+ and
CC       G-. G+ orientation provides S-U fibers whereas G- provides S'-U'
CC       fibers. S-U and S'-U' dont have the same host range (e.g. respectively
CC       E.coli and C.freundii).
CC   -!- SIMILARITY: Belongs to the tfa family. {ECO:0000305}.
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DR   EMBL; AF083977; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_602302.1; NC_000929.1.
DR   SMR; P0DJY5; -.
DR   GeneID; 2636259; -.
DR   KEGG; vg:2636259; -.
DR   Proteomes; UP000002611; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0098024; C:virus tail, fiber; IEA:UniProtKB-KW.
DR   GO; GO:0098671; P:adhesion receptor-mediated virion attachment to host cell; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0098678; P:viral tropism switching; IEA:UniProtKB-KW.
DR   GO; GO:0098004; P:virus tail fiber assembly; IEA:UniProtKB-KW.
DR   InterPro; IPR003458; Phage_T4_Gp38_tail_assem.
DR   Pfam; PF02413; Caudo_TAP; 1.
PE   2: Evidence at transcript level;
KW   Host cytoplasm; Host-virus interaction; Late protein; Reference proteome;
KW   Viral attachment to host adhesion receptor; Viral attachment to host cell;
KW   Viral receptor tropism switching; Viral release from host cell;
KW   Viral tail assembly; Viral tail fiber assembly; Viral tail fiber protein;
KW   Viral tail protein; Virion; Virus entry into host cell.
FT   CHAIN           1..177
FT                   /note="Tail fiber assembly protein U'"
FT                   /id="PRO_0000429064"
SQ   SEQUENCE   177 AA;  20698 MW;  A7E29392E37B0137 CRC64;
     MMHLKNITAG NPKTKEQYQL TKQFNIKWLY TEDGKNWYEE QKNFQPDTLK MVYDHNGVII
     CIEKDVSAIN PEGANVVEVP DITANRRADI SGKWMFKDGV VIKRTYTEEE QRQQAENEKQ
     SLLQLVRDKT QLWDSQLRLG IISDENKQKL TEWMLYAQKV ESTDTSSLPV TFPEQPE