U375F_CAEEL
ID U375F_CAEEL Reviewed; 124 AA.
AC O45944;
DT 05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=UPF0375 protein Y45F10C.4;
DE Flags: Precursor;
GN ORFNames=Y45F10C.4;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2]
RP GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-62, AND IDENTIFICATION BY MASS
RP SPECTROMETRY.
RC STRAIN=Bristol N2;
RX PubMed=12754521; DOI=10.1038/nbt829;
RA Kaji H., Saito H., Yamauchi Y., Shinkawa T., Taoka M., Hirabayashi J.,
RA Kasai K., Takahashi N., Isobe T.;
RT "Lectin affinity capture, isotope-coded tagging and mass spectrometry to
RT identify N-linked glycoproteins.";
RL Nat. Biotechnol. 21:667-672(2003).
RN [3]
RP GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-62, AND IDENTIFICATION BY MASS
RP SPECTROMETRY.
RC STRAIN=Bristol N2;
RX PubMed=17761667; DOI=10.1074/mcp.m600392-mcp200;
RA Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T.,
RA Taoka M., Takahashi N., Isobe T.;
RT "Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis
RT elegans and suggests an atypical translocation mechanism for integral
RT membrane proteins.";
RL Mol. Cell. Proteomics 6:2100-2109(2007).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the UPF0375 family. {ECO:0000305}.
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DR EMBL; Z99273; CAB16479.1; -; Genomic_DNA.
DR PIR; T26928; T26928.
DR RefSeq; NP_502640.1; NM_070239.5.
DR AlphaFoldDB; O45944; -.
DR BioGRID; 43419; 2.
DR STRING; 6239.Y45F10C.4; -.
DR iPTMnet; O45944; -.
DR EPD; O45944; -.
DR PaxDb; O45944; -.
DR PeptideAtlas; O45944; -.
DR EnsemblMetazoa; Y45F10C.4.1; Y45F10C.4.1; WBGene00012880.
DR GeneID; 178335; -.
DR KEGG; cel:CELE_Y45F10C.4; -.
DR UCSC; Y45F10C.4; c. elegans.
DR CTD; 178335; -.
DR WormBase; Y45F10C.4; CE16638; WBGene00012880; -.
DR HOGENOM; CLU_2028770_0_0_1; -.
DR InParanoid; O45944; -.
DR OrthoDB; 1898993at2759; -.
DR PRO; PR:O45944; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00012880; Expressed in adult organism and 2 other tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR009981; DUF1505.
DR Pfam; PF07403; DUF1505; 1.
PE 1: Evidence at protein level;
KW Glycoprotein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..124
FT /note="UPF0375 protein Y45F10C.4"
FT /id="PRO_0000248528"
FT CARBOHYD 36
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 62
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000269|PubMed:12754521,
FT ECO:0000269|PubMed:17761667"
SQ SEQUENCE 124 AA; 13557 MW; 53BDB092CF8D9305 CRC64;
MNFLPSTVLL LSFVVAIISG SFSSISEEWK AVCECNLSKL NNHAKTGNCK TTALWKVTSD
TNCTASEYLK ITVFPANDDP LNRVEQCTMT PCDQTEKTPA DCNVAFSAAK LAEIAKEEKS
KMII