ID   U376A_CAEEL             Reviewed;         203 AA.
AC   O01454;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 4.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=UPF0376 protein C03G6.5;
DE   Flags: Precursor;
GN   ORFNames=C03G6.5;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-84, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RC   STRAIN=Bristol N2;
RX   PubMed=12754521; DOI=10.1038/nbt829;
RA   Kaji H., Saito H., Yamauchi Y., Shinkawa T., Taoka M., Hirabayashi J.,
RA   Kasai K., Takahashi N., Isobe T.;
RT   "Lectin affinity capture, isotope-coded tagging and mass spectrometry to
RT   identify N-linked glycoproteins.";
RL   Nat. Biotechnol. 21:667-672(2003).
RN   [3]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-84, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RX   PubMed=15888633; DOI=10.1093/glycob/cwi075;
RA   Fan X., She Y.-M., Bagshaw R.D., Callahan J.W., Schachter H., Mahuran D.J.;
RT   "Identification of the hydrophobic glycoproteins of Caenorhabditis
RT   elegans.";
RL   Glycobiology 15:952-964(2005).
RN   [4]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-32 AND ASN-84, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=Bristol N2;
RX   PubMed=17761667; DOI=10.1074/mcp.m600392-mcp200;
RA   Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T.,
RA   Taoka M., Takahashi N., Isobe T.;
RT   "Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis
RT   elegans and suggests an atypical translocation mechanism for integral
RT   membrane proteins.";
RL   Mol. Cell. Proteomics 6:2100-2109(2007).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0376 family. {ECO:0000305}.
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DR   EMBL; FO080297; CCD62706.1; -; Genomic_DNA.
DR   RefSeq; NP_504881.3; NM_072480.3.
DR   AlphaFoldDB; O01454; -.
DR   STRING; 6239.C03G6.5; -.
DR   iPTMnet; O01454; -.
DR   EPD; O01454; -.
DR   PaxDb; O01454; -.
DR   PeptideAtlas; O01454; -.
DR   PRIDE; O01454; -.
DR   EnsemblMetazoa; C03G6.5.1; C03G6.5.1; WBGene00015393.
DR   GeneID; 179123; -.
DR   KEGG; cel:CELE_C03G6.5; -.
DR   UCSC; C03G6.5; c. elegans.
DR   CTD; 179123; -.
DR   WormBase; C03G6.5; CE45476; WBGene00015393; -.
DR   eggNOG; ENOG502THJ5; Eukaryota.
DR   GeneTree; ENSGT00970000195826; -.
DR   HOGENOM; CLU_078890_1_0_1; -.
DR   InParanoid; O01454; -.
DR   OrthoDB; 1767442at2759; -.
DR   PhylomeDB; O01454; -.
DR   PRO; PR:O01454; -.
DR   Proteomes; UP000001940; Chromosome V.
DR   Bgee; WBGene00015393; Expressed in larva and 2 other tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002542; DUF19.
DR   InterPro; IPR016638; UPF0376.
DR   Pfam; PF01579; DUF19; 1.
DR   PIRSF; PIRSF015697; UCP015697; 1.
PE   1: Evidence at protein level;
KW   Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..203
FT                   /note="UPF0376 protein C03G6.5"
FT                   /id="PRO_0000248555"
FT   CARBOHYD        32
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000269|PubMed:17761667"
FT   CARBOHYD        84
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000269|PubMed:12754521,
FT                   ECO:0000269|PubMed:15888633, ECO:0000269|PubMed:17761667"
FT   CARBOHYD        188
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   203 AA;  22819 MW;  385573D71D850AB2 CRC64;
     MIGFLKFALI GTVLLGVANG ASVATASAKG SNCTVQDGYA ALMCLVRLSD FAEKVDNLDM
     NDKTKLKEFK RSCDSLHSCY SNLNCTTKSD DEKDKYVESI KQYCDAVVYV SDGFSKCSDK
     LNEKKSKCFD DWDPIPNKIH LEEDEAKIEK IKNEACKTYF GKDDCMKKEI TETCGKEEWD
     SFRKQFVNLS GGLVSKCDFS RFE