ID   U376C_CAEEL             Reviewed;         201 AA.
AC   Q22957;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 2.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=UPF0376 protein F10G2.1;
GN   ORFNames=F10G2.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-32, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RC   STRAIN=Bristol N2;
RX   PubMed=12754521; DOI=10.1038/nbt829;
RA   Kaji H., Saito H., Yamauchi Y., Shinkawa T., Taoka M., Hirabayashi J.,
RA   Kasai K., Takahashi N., Isobe T.;
RT   "Lectin affinity capture, isotope-coded tagging and mass spectrometry to
RT   identify N-linked glycoproteins.";
RL   Nat. Biotechnol. 21:667-672(2003).
RN   [3]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-32, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RC   STRAIN=Bristol N2;
RX   PubMed=17761667; DOI=10.1074/mcp.m600392-mcp200;
RA   Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T.,
RA   Taoka M., Takahashi N., Isobe T.;
RT   "Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis
RT   elegans and suggests an atypical translocation mechanism for integral
RT   membrane proteins.";
RL   Mol. Cell. Proteomics 6:2100-2109(2007).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0376 family. {ECO:0000305}.
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DR   EMBL; FO080316; CCD62809.1; -; Genomic_DNA.
DR   RefSeq; NP_504867.1; NM_072466.3.
DR   AlphaFoldDB; Q22957; -.
DR   STRING; 6239.F10G2.1; -.
DR   iPTMnet; Q22957; -.
DR   EPD; Q22957; -.
DR   PaxDb; Q22957; -.
DR   PeptideAtlas; Q22957; -.
DR   EnsemblMetazoa; F10G2.1.1; F10G2.1.1; WBGene00017362.
DR   EnsemblMetazoa; F10G2.1.2; F10G2.1.2; WBGene00017362.
DR   GeneID; 179122; -.
DR   KEGG; cel:CELE_F10G2.1; -.
DR   UCSC; F10G2.1; c. elegans.
DR   CTD; 179122; -.
DR   WormBase; F10G2.1; CE27945; WBGene00017362; -.
DR   eggNOG; ENOG502THJ5; Eukaryota.
DR   GeneTree; ENSGT00970000195826; -.
DR   HOGENOM; CLU_078890_1_0_1; -.
DR   InParanoid; Q22957; -.
DR   OMA; WDPFPDA; -.
DR   OrthoDB; 1767442at2759; -.
DR   PhylomeDB; Q22957; -.
DR   PRO; PR:Q22957; -.
DR   Proteomes; UP000001940; Chromosome V.
DR   Bgee; WBGene00017362; Expressed in adult organism and 3 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR002542; DUF19.
DR   InterPro; IPR016638; UPF0376.
DR   Pfam; PF01579; DUF19; 1.
DR   PIRSF; PIRSF015697; UCP015697; 1.
PE   1: Evidence at protein level;
KW   Glycoprotein; Membrane; Reference proteome; Signal-anchor; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..201
FT                   /note="UPF0376 protein F10G2.1"
FT                   /id="PRO_0000248557"
FT   TOPO_DOM        1..3
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        4..24
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        25..201
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        32
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000269|PubMed:12754521,
FT                   ECO:0000269|PubMed:17761667"
FT   CARBOHYD        124
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   201 AA;  22989 MW;  596AFD3C712007DA CRC64;
     MKHFLLLAII GILFLGSTYG ASVATEKLKA SNCTKTEGFQ AIACVLRMAD FAQKIEKLDM
     DDKNQVNEFE KSCVSFANCF ETLQCGPEDP AEKKINNMIK NYCDAVVYVA KDFADCSEKL
     ENKNSTCYQN WDPFPDAIDE ETDEKKKEKM LQEACKNYFG KDNCLKKEIT EKCSETEWKG
     FRDHFIGISN ILLECDFRNI Q