ID   U496D_ARATH             Reviewed;         385 AA.
AC   P0DI78; Q56XE6; Q8GXJ7; Q9XF11;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=UPF0496 protein At3g28290;
DE   AltName: Full=Protein At14a;
GN   OrderedLocusNames=At3g28290; ORFNames=MZF16.7;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND SUBCELLULAR LOCATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=10196471; DOI=10.1016/s0378-1119(99)00068-2;
RA   Nagpal P., Quatrano R.S.;
RT   "Isolation and characterization of a cDNA clone from Arabidopsis thaliana
RT   with partial sequence similarity to integrins.";
RL   Gene 230:33-40(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA   Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT   features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT   clones.";
RL   DNA Res. 7:217-221(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 19-385.
RC   STRAIN=cv. Columbia;
RX   PubMed=11910074; DOI=10.1126/science.1071006;
RA   Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA   Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA   Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA   Shinagawa A., Shinozaki K.;
RT   "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL   Science 296:141-145(2002).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 19-385.
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:10196471}; Multi-
CC       pass membrane protein {ECO:0000269|PubMed:10196471}.
CC   -!- TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:10196471}.
CC   -!- SIMILARITY: Belongs to the UPF0496 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC42823.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AF126374; AAD26355.1; -; mRNA.
DR   EMBL; AP002051; BAB02619.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE77428.1; -; Genomic_DNA.
DR   EMBL; AY057599; AAL14394.1; -; mRNA.
DR   EMBL; AY124839; AAM70548.1; -; mRNA.
DR   EMBL; AK118201; BAC42823.1; ALT_INIT; mRNA.
DR   EMBL; AK221728; BAD93736.1; -; mRNA.
DR   RefSeq; NP_189469.1; NM_113748.5.
DR   RefSeq; NP_189470.1; NM_113749.4.
DR   AlphaFoldDB; P0DI78; -.
DR   SMR; P0DI78; -.
DR   BioGRID; 7786; 2.
DR   STRING; 3702.AT3G28290.1; -.
DR   MetOSite; P0DI78; -.
DR   PaxDb; P0DI78; -.
DR   PRIDE; P0DI78; -.
DR   EnsemblPlants; AT3G28290.1; AT3G28290.1; AT3G28290.
DR   EnsemblPlants; AT3G28300.1; AT3G28300.1; AT3G28300.
DR   GeneID; 822455; -.
DR   GeneID; 822457; -.
DR   Gramene; AT3G28290.1; AT3G28290.1; AT3G28290.
DR   Gramene; AT3G28300.1; AT3G28300.1; AT3G28300.
DR   KEGG; ath:AT3G28290; -.
DR   KEGG; ath:AT3G28300; -.
DR   Araport; AT3G28290; -.
DR   eggNOG; ENOG502QVAQ; Eukaryota.
DR   HOGENOM; CLU_044778_1_0_1; -.
DR   OrthoDB; 1379181at2759; -.
DR   PhylomeDB; P0DI78; -.
DR   PRO; PR:P0DI78; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; P0DI78; baseline and differential.
DR   Genevisible; P0DI78; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007749; DUF677.
DR   PANTHER; PTHR31113; PTHR31113; 1.
DR   Pfam; PF05055; DUF677; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..385
FT                   /note="UPF0496 protein At3g28290"
FT                   /id="PRO_0000306889"
FT   TRANSMEM        217..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        242..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   COILED          138..214
FT                   /evidence="ECO:0000255"
FT   COILED          267..294
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   385 AA;  42955 MW;  3EA2EA4AE6ADD50C CRC64;
     MVLSKENMLK YSAHLRAYNS ACGDHPELKS FDSELQQKTS NLINSFTSDA KTGLVPLPQH
     AAYKEFTKHL AEVNQQVSDY IIGYGEVVWE NSTLRSLVET YFESAKKTLD IAENVTEYVD
     EAKRGERYIV AAVAQFEKDK ENDVGKKTKR YENTLRELKK FEAMGNPFDG DKFTTLFKLM
     HKEQESLLER VRETKEKLDE ELKNIEMEIS SRKKWSIISN VLFIGAFVAV AVGSMVLVCT
     GVGAGVGVAG LLSLPLIAIG WVGVHTILEN KIQAREKQEE ALKKAHRIAN EMDKGMETDK
     VDMNSISGKV HALKSKITSM LNAVKDATED GANEVDTKQV METLTGDVVE LTEDIKAVGD
     DVAKYSKMIE ETSYHVLQKI TGSGK