ID   U496F_ARATH             Reviewed;         398 AA.
AC   Q9LVR4; A0MFR6;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=UPF0496 protein At5g66660;
GN   OrderedLocusNames=At5g66660; ORFNames=MSN2.4;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT   features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:31-63(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0496 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABK28300.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AB018119; BAA97272.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED98247.1; -; Genomic_DNA.
DR   EMBL; DQ447112; ABE65589.1; -; Genomic_DNA.
DR   EMBL; DQ653393; ABK28300.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; NP_201467.1; NM_126064.2.
DR   AlphaFoldDB; Q9LVR4; -.
DR   SMR; Q9LVR4; -.
DR   BioGRID; 22040; 1.
DR   IntAct; Q9LVR4; 1.
DR   STRING; 3702.AT5G66660.1; -.
DR   PaxDb; Q9LVR4; -.
DR   PRIDE; Q9LVR4; -.
DR   EnsemblPlants; AT5G66660.1; AT5G66660.1; AT5G66660.
DR   GeneID; 836798; -.
DR   Gramene; AT5G66660.1; AT5G66660.1; AT5G66660.
DR   KEGG; ath:AT5G66660; -.
DR   Araport; AT5G66660; -.
DR   TAIR; locus:2173639; AT5G66660.
DR   eggNOG; ENOG502QVAQ; Eukaryota.
DR   HOGENOM; CLU_044778_0_0_1; -.
DR   InParanoid; Q9LVR4; -.
DR   OMA; GFTEKME; -.
DR   OrthoDB; 1030078at2759; -.
DR   PhylomeDB; Q9LVR4; -.
DR   PRO; PR:Q9LVR4; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9LVR4; baseline and differential.
DR   Genevisible; Q9LVR4; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007749; DUF677.
DR   PANTHER; PTHR31113; PTHR31113; 1.
DR   Pfam; PF05055; DUF677; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..398
FT                   /note="UPF0496 protein At5g66660"
FT                   /id="PRO_0000306891"
FT   TRANSMEM        240..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        263..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   398 AA;  44954 MW;  A3E17AE82D3F9E3A CRC64;
     MEFCGCLSEL MNGESSSKRN GPSTLPVKEV RTDMRSKYSS DLSSYTSACK KDSNLKSFDS
     SLHQRTNIII TSLAARAETQ SLNLDSLMEV YGFLLELNQN AVRVIIESRE DVWKNKDLKS
     LVDVYFKSTS KTLDFCNTVE NCVKRTEISQ LIIRFAVKQF EAESVDTDLG GDKKKKKYTK
     TLEELNKFKA MGDPFDGELV TQFDSVYDQQ VLFLEELRKQ RRKLDKKQRN VKTLRTVSNV
     FFATAYVSVL VLSVVATTMS APPVVCAVAS GSTAPIEITG KWFSQMWKKY EKAVKRQRGL
     VLTMESRVQV NNEAMKNIRS DVDELRSWVS SILETVDFAV EREEEEEAMG LAMQGIKKHV
     DGFTEKMEEV GENAAKCSKF IALGRLLVLE HILGLPAN