U496H_ARATH
ID U496H_ARATH Reviewed; 412 AA.
AC Q8GW16;
DT 02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=UPF0496 protein At5g66675;
GN OrderedLocusNames=At5g66675; ORFNames=MSN2.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the UPF0496 family. {ECO:0000305}.
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DR EMBL; AB018119; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED98250.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM70078.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM70079.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM70080.1; -; Genomic_DNA.
DR EMBL; AK119145; BAC43715.1; -; mRNA.
DR EMBL; BT005355; AAO63419.1; -; mRNA.
DR RefSeq; NP_001331713.1; NM_001345799.1.
DR RefSeq; NP_001331714.1; NM_001345798.1.
DR RefSeq; NP_001331715.1; NM_001345800.1.
DR RefSeq; NP_850929.1; NM_180598.3.
DR AlphaFoldDB; Q8GW16; -.
DR SMR; Q8GW16; -.
DR PaxDb; Q8GW16; -.
DR PRIDE; Q8GW16; -.
DR ProteomicsDB; 228557; -.
DR EnsemblPlants; AT5G66675.1; AT5G66675.1; AT5G66675.
DR EnsemblPlants; AT5G66675.2; AT5G66675.2; AT5G66675.
DR EnsemblPlants; AT5G66675.3; AT5G66675.3; AT5G66675.
DR EnsemblPlants; AT5G66675.4; AT5G66675.4; AT5G66675.
DR GeneID; 836800; -.
DR Gramene; AT5G66675.1; AT5G66675.1; AT5G66675.
DR Gramene; AT5G66675.2; AT5G66675.2; AT5G66675.
DR Gramene; AT5G66675.3; AT5G66675.3; AT5G66675.
DR Gramene; AT5G66675.4; AT5G66675.4; AT5G66675.
DR KEGG; ath:AT5G66675; -.
DR Araport; AT5G66675; -.
DR TAIR; locus:1005716837; AT5G66675.
DR eggNOG; ENOG502QVAQ; Eukaryota.
DR HOGENOM; CLU_044778_0_0_1; -.
DR InParanoid; Q8GW16; -.
DR OMA; MESMMQK; -.
DR OrthoDB; 1134085at2759; -.
DR PhylomeDB; Q8GW16; -.
DR PRO; PR:Q8GW16; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q8GW16; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR007749; DUF677.
DR PANTHER; PTHR31113; PTHR31113; 1.
DR Pfam; PF05055; DUF677; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..412
FT /note="UPF0496 protein At5g66675"
FT /id="PRO_0000306893"
FT TRANSMEM 240..260
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 263..283
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 314..348
FT /evidence="ECO:0000255"
FT COMPBIAS 9..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 412 AA; 46371 MW; 43064E6FC3C43303 CRC64;
MFLGMFSKTM EDKSNSSRNR TNNTPLPQQI RTDMGSLYSA DLTAYNSACR EDPDLQSFDS
SLHQRTNRVI NSLASGAQTR SLSFDALIEV SGCLLEMNQE VVRFIIESKE DVWDNKDLTC
LVNAYFDSSI KTLDFCNAVD NCVKRARIGQ MLLQFALKQF EMESSGSNKS VEPGTNKYAK
TLEELNKFKA SGDPFDGDFF MLLESVYEQQ VMLLEILHKQ KRKLDKKLKN IKYWKKISNV
VFVTAFVSVL IFSVVAAAVA APPVVTALAA ALAVPIGSIG KWCNHLWKKY ETAVKGQKDI
VLSMRIGAYV TMKDMDNIRV HVDKLKIEME SMMQKVDFAL KEKEEEVAVR LSMHEISKKF
DVFTERIEEV GDNATKCSKN ITLARTIVLR HILSFPSSSD SGQGNLIEAI TL
