U496M_ARATH
ID U496M_ARATH Reviewed; 382 AA.
AC Q9LT84; B3DN90; Q3E7M1; Q3EB43;
DT 02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 02-OCT-2007, sequence version 2.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=UPF0496 protein At3g19330;
GN OrderedLocusNames=At3g19330; ORFNames=MLD14.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA De Los Reyes C., Quan R., Chen H., Bautista V.R., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=1;
CC IsoId=Q9LT84-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9LT84-2; Sequence=VSP_028565, VSP_028566;
CC Name=3;
CC IsoId=Q9LT84-3; Sequence=VSP_028565, VSP_028567;
CC -!- MISCELLANEOUS: [Isoform 2]: May be due to a competing acceptor splice
CC site. {ECO:0000305}.
CC -!- MISCELLANEOUS: [Isoform 3]: May be due to a competing acceptor splice
CC site. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the UPF0496 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB02457.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB025624; BAB02457.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE76224.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE76225.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE76226.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM64647.1; -; Genomic_DNA.
DR EMBL; BT032878; ACD89068.1; -; mRNA.
DR RefSeq; NP_001326660.1; NM_001338392.1. [Q9LT84-1]
DR RefSeq; NP_188564.2; NM_112820.3. [Q9LT84-1]
DR RefSeq; NP_974339.1; NM_202610.2. [Q9LT84-2]
DR RefSeq; NP_974340.1; NM_202611.1. [Q9LT84-3]
DR AlphaFoldDB; Q9LT84; -.
DR SMR; Q9LT84; -.
DR STRING; 3702.AT3G19330.1; -.
DR iPTMnet; Q9LT84; -.
DR PaxDb; Q9LT84; -.
DR PRIDE; Q9LT84; -.
DR ProteomicsDB; 228728; -. [Q9LT84-1]
DR EnsemblPlants; AT3G19330.1; AT3G19330.1; AT3G19330. [Q9LT84-1]
DR EnsemblPlants; AT3G19330.2; AT3G19330.2; AT3G19330. [Q9LT84-2]
DR EnsemblPlants; AT3G19330.3; AT3G19330.3; AT3G19330. [Q9LT84-3]
DR EnsemblPlants; AT3G19330.4; AT3G19330.4; AT3G19330. [Q9LT84-1]
DR GeneID; 821467; -.
DR Gramene; AT3G19330.1; AT3G19330.1; AT3G19330. [Q9LT84-1]
DR Gramene; AT3G19330.2; AT3G19330.2; AT3G19330. [Q9LT84-2]
DR Gramene; AT3G19330.3; AT3G19330.3; AT3G19330. [Q9LT84-3]
DR Gramene; AT3G19330.4; AT3G19330.4; AT3G19330. [Q9LT84-1]
DR KEGG; ath:AT3G19330; -.
DR Araport; AT3G19330; -.
DR TAIR; locus:2090624; AT3G19330.
DR eggNOG; KOG0123; Eukaryota.
DR InParanoid; Q9LT84; -.
DR OMA; CNWAFDI; -.
DR PhylomeDB; Q9LT84; -.
DR PRO; PR:Q9LT84; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LT84; baseline and differential.
DR Genevisible; Q9LT84; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR007749; DUF677.
DR PANTHER; PTHR31113; PTHR31113; 1.
DR Pfam; PF05055; DUF677; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..382
FT /note="UPF0496 protein At3g19330"
FT /id="PRO_0000306898"
FT TRANSMEM 222..242
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 246..266
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 228..259
FT /note="Missing (in isoform 2 and isoform 3)"
FT /evidence="ECO:0000303|Ref.3"
FT /id="VSP_028565"
FT VAR_SEQ 378..382
FT /note="Missing (in isoform 3)"
FT /evidence="ECO:0000305"
FT /id="VSP_028567"
FT VAR_SEQ 378
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.3"
FT /id="VSP_028566"
SQ SEQUENCE 382 AA; 43009 MW; CF6DE208B48CBB28 CRC64;
MRNCLSFNPA SPEASLGDDP LPHPSLESGV ASTSRNDASI SSPTFNLSRE LAHAFQTPSY
HDVRSRVHVV VDLTQIHHRL IQPDIELLLS QVLQPNKECV QEAIRHVKQT TLTNLVSTYF
QHSEDATRLC LNLYQNVHSA RHHLYTPLLD LFNIFPGDSL PAIDESLCDL AFDVFLKLDT
FENPFSSPES YSFRDTQLCF SQLKHNLDRR LRKSRSRVRL IHHATAGSSL CLVAAVVAVA
ASAVVIASHA LPILLVVAGP LCSPYLPHSF KRKELTNICQ LNAASKGTFV LNKDLDTIDR
LVSRLHTGIE YDKFLIRLGL ERGRDVHSIQ EILKLLRKSH LPLTHQLKDL EDHICLWFTN
VNKARSLLLT EIHLPRPSHV IL
