ID   U507_CANAL              Reviewed;        1189 AA.
AC   Q5A0J0; A0A1D8PGR4;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2017, sequence version 2.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=UPF0507 protein C2_02840C_A;
GN   OrderedLocusNames=CAALFM_C202840CA; ORFNames=CaO19.13243, CaO19.5821;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- SIMILARITY: Belongs to the UPF0507 family. {ECO:0000305}.
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DR   EMBL; CP017624; AOW27321.1; -; Genomic_DNA.
DR   RefSeq; XP_715362.2; XM_710269.2.
DR   AlphaFoldDB; Q5A0J0; -.
DR   SMR; Q5A0J0; -.
DR   STRING; 237561.Q5A0J0; -.
DR   PRIDE; Q5A0J0; -.
DR   GeneID; 3642976; -.
DR   KEGG; cal:CAALFM_C202840CA; -.
DR   CGD; CAL0000186581; orf19.13243.
DR   VEuPathDB; FungiDB:C2_02840C_A; -.
DR   eggNOG; ENOG502R3ZQ; Eukaryota.
DR   HOGENOM; CLU_008912_0_0_1; -.
DR   InParanoid; Q5A0J0; -.
DR   OrthoDB; 203294at2759; -.
DR   PRO; PR:Q5A0J0; -.
DR   Proteomes; UP000000559; Chromosome 2.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0005769; C:early endosome; IBA:GO_Central.
DR   GO; GO:0005770; C:late endosome; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0030133; C:transport vesicle; IBA:GO_Central.
DR   GO; GO:0097422; C:tubular endosome; IBA:GO_Central.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:GO_Central.
DR   GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR   GO; GO:0045022; P:early endosome to late endosome transport; IBA:GO_Central.
DR   Gene3D; 1.20.1050.80; -; 1.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR003123; VPS9.
DR   InterPro; IPR037191; VPS9_dom_sf.
DR   Pfam; PF02204; VPS9; 1.
DR   SUPFAM; SSF109993; SSF109993; 1.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS51205; VPS9; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..1189
FT                   /note="UPF0507 protein C2_02840C_A"
FT                   /id="PRO_0000311651"
FT   DOMAIN          321..471
FT                   /note="VPS9"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00550"
SQ   SEQUENCE   1189 AA;  139090 MW;  D00C6F38412B1D08 CRC64;
     MTSTNKSISH LPILHNPFLN CLFNNPQYFK SPLKGVVDEL QSNHTNFTIL VPPAHVLNEY
     YDPTTESSNS KTLLKELCYN NEDFIRSHII NTASPVSSTI TPISKEQSVI YNTLNNKQIL
     IKNRIIYTGK GFRRSLKLKT LSIQYFSSFC DYFPKRSKFM IIYIESTLFG GIPPRKMLPP
     LPEVRETNKT DKDIDSVTFE KLLRSFPLLS KAVSDKFYRL FHHNNYQFRV LRYKNRKKLS
     HIKLEFQKIL QEAFSIISDS VNVDNPNSEQ TYNLINHIIS MYPGIDLNKL VHEYVELNLY
     DVLWSQLIFQ FNCPNDDKEA YDPEAILILT KEKYEKLSCL SLNQLDIPVN KPWLMNELHE
     RISLGVQEFE KLADSSIMNS AAKTQVVYST FRILTQRKNG NIDPVINADT LIGLLIMVMV
     HSKIENIEAH IYYIKHFNSI DNTNDGQFNY IMSNLDAVLF HFSKKESGYL DLIENSKKNY
     EIWNAIKNND LEKVESIIEL VNNEYPETEL PENHFLKSKN INGESCLMFA IKTKRYEIYD
     CLINSNPNWI PIDSILFEKN VMTNQNLLMC ALIEETDYKI IDDLVDIILN NATLEEQTMY
     FNMTDISGRS VGHYLFHNYK LISKIGHLID WEKKDNNSHT PLFSLCRCYD HPEYVELIRA
     GFNCVYKKYG ETGVDYDKHV DKSGNTLLHV LLKGIPESKM LSNSNNLVNV NQLNQRCLSP
     LMVYVKYNRL ENLKEILHDS RLDFLGEDFK NYYNVFDYLS FSALKSTKSE NFQNIENAVF
     NYYLQNYFPR HATENVAALN AKYDGGKKDW LIFFKNGDGF CNYKSLRNIK QILYLIKLKQ
     PLSTFPSEES FWKNYGFGIS TSPMFHKVRI NRLIDDFNLL FEGLTFQESI NQSEFFKTFL
     TEYTKETSIF ESKQRIGEQL DFDKQSLGEV TYKLNQIQEI EYFLEYSLNN FQKYAYLFAR
     LAKLVCIGDS KQVDCRNVLD TIMYRFNKTT VFDDIFTYSE VNNQAGTLGV AREYFYWIQM
     HGDELLHSIQ KLVSDINSWK QMYYSICHIN SELKLMEPHN TVSQESQDNS NGQELLSRRD
     SSLSINPIPE EELEDDNLGF LSNFVGTSKK ARYKKLVVEK SEIVKNIMKL NLEIKWSHEL
     IAAEISDFLK FRTEFLRFGI KRYISEEIKS LKQRSTELSK YVFLVRKDK