ID   U518_BRUMA              Reviewed;        1016 AA.
AC   A8P7J8;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=FHIP family protein Bm1_18400;
GN   ORFNames=Bm1_18400;
OS   Brugia malayi (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=6279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17885136; DOI=10.1126/science.1145406;
RA   Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA   Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA   Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA   Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA   Pop M., White O., Barton G.J., Carlow C.K.S., Crawford M.J., Daub J.,
RA   Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA   Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.-W.,
RA   Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA   McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA   Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA   Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA   Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA   Blaxter M.L., Scott A.L.;
RT   "Draft genome of the filarial nematode parasite Brugia malayi.";
RL   Science 317:1756-1760(2007).
CC   -!- SIMILARITY: Belongs to the FHIP family. {ECO:0000305}.
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DR   EMBL; DS238807; EDP36017.1; -; Genomic_DNA.
DR   RefSeq; XP_001895137.1; XM_001895102.1.
DR   AlphaFoldDB; A8P7J8; -.
DR   GeneID; 6098585; -.
DR   CTD; 6098585; -.
DR   WormBase; Bm11307; BM42660; WBGene00231568; -.
DR   InParanoid; A8P7J8; -.
DR   OrthoDB; 141539at2759; -.
DR   Proteomes; UP000006672; Unassembled WGS sequence.
DR   InterPro; IPR019384; FHIP.
DR   InterPro; IPR045669; FHIP_C.
DR   InterPro; IPR045668; FHIP_KELAA_motif.
DR   PANTHER; PTHR21705; PTHR21705; 1.
DR   Pfam; PF19314; DUF5917; 1.
DR   Pfam; PF19311; KELAA; 1.
DR   Pfam; PF10257; RAI16-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..1016
FT                   /note="FHIP family protein Bm1_18400"
FT                   /id="PRO_0000379002"
FT   REGION          586..608
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          757..778
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        757..776
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1016 AA;  114110 MW;  4EBCC30E9F7B5A31 CRC64;
     MRRWFSKLGS TSLASTSRVT AFSSSESAAV EQLADSSIPP PITPFIIAKP DIHWNVDFAS
     DPCSWESCFD AHWEAAEKLL ENEEEISYEK VITVFQHLNC TVQLLMMEAN AQPESAIGSI
     LDRHFTHQIM ERVVDWAIAA PHFLTPTCQV NMIGLYEVIV GESHTQNHCL LVHKPMLLPL
     LKLLDWCRKS AEKRNFTPSN TDRHFVLLLN QICTKLAEDT TLLHFFFDFD DDCDEQFLVF
     SLLIPYLYDS GEVGQLARDA LLLILSVSRR LKRVATFIAV KSNFCPVVAT GLSGCFSQLS
     RSFGSMLYVS DSWHKINADD IDSYSSLLDF HSSLIFCNAV IQVAHGYVVS QVIRYVYHGF
     LLPVVLPSLL QGGQDELISS TAYYHLCLDS VTETVLVQTI VKLLLNESCE SNKTVLDVIV
     ERISAGNRLS QVSLSLVRTL IDLRCEDIMF DLVFKYLLPC TFLQPNQTLH LKNQMYVRTA
     AQTLLTFVPE CTYKSSALCS QETLHIYLSE CRNYVQETTD ACCEKWVWSY DGRSPFFMPK
     INSDEESATN SNGAFVRHSS VRSSMASARN GLNRYFVSRN AHITADSLRQ HTPPPELGEQ
     ESSSRSSFPY DIADSSLVLD DEGDELIIPA LTPTSLMMMT SSSDYFQFAY GELSETDTEA
     INPSVVSMSG APAQSISDKA SLASTSANCD TDIEMARSFV LRGWGQIEDT DTFMALMDRV
     PASKIKHSLE ENMALIDSRI QYLEELKAEA KLQDLESDGF KSDTNNDNDD EDPAPLGKPI
     ECFGNQGVGP FLESIMRSLE NMLDNSLYVT LQTTSVLAAL ASYPQPLIAH YLFDQRMLLQ
     PNVKNLFKVM DSLKTQIDAY ASSLDGFDVL LERGIKFLRS RAERYEKVVE SSRRLRSSES
     FSRNGNMEGR SSSRGLFNRF RSSNNKRLYP SNDSSHPHEF RIYTHKAIES RDVTLDHARA
     KQFVFAAIIL SQFCQELAAT VLQHSTVVPR PKVSPAKDYL RREVNSAGKD ANCCAD