U518_DROGR
ID U518_DROGR Reviewed; 1066 AA.
AC B4JQY3;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 47.
DE RecName: Full=FHIP family protein GH13096;
GN ORFNames=GH13096;
OS Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Hawaiian Drosophila.
OX NCBI_TaxID=7222;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15287-2541.00;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SIMILARITY: Belongs to the FHIP family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH916372; EDV99313.1; -; Genomic_DNA.
DR RefSeq; XP_001993388.1; XM_001993352.1.
DR AlphaFoldDB; B4JQY3; -.
DR STRING; 7222.FBpp0147002; -.
DR EnsemblMetazoa; FBtr0148510; FBpp0147002; FBgn0120573.
DR GeneID; 6566600; -.
DR KEGG; dgr:6566600; -.
DR eggNOG; KOG3695; Eukaryota.
DR HOGENOM; CLU_007807_0_0_1; -.
DR InParanoid; B4JQY3; -.
DR OMA; CLDWDSG; -.
DR OrthoDB; 141539at2759; -.
DR PhylomeDB; B4JQY3; -.
DR Proteomes; UP000001070; Unassembled WGS sequence.
DR InterPro; IPR019384; FHIP.
DR InterPro; IPR045669; FHIP_C.
DR InterPro; IPR045668; FHIP_KELAA_motif.
DR PANTHER; PTHR21705; PTHR21705; 1.
DR Pfam; PF19314; DUF5917; 1.
DR Pfam; PF19311; KELAA; 1.
DR Pfam; PF10257; RAI16-like; 1.
PE 3: Inferred from homology;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..1066
FT /note="FHIP family protein GH13096"
FT /id="PRO_0000379009"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 647..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 827..885
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 942..1010
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..688
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 827..871
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 512
FT /note="Phosphoserine"
FT /evidence="ECO:0000250"
FT MOD_RES 829
FT /note="Phosphoserine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 1066 AA; 117516 MW; 7700DC1EF88FED8C CRC64;
MSWLRTSPLR QSLTRNSGGN GSGGSGNSGN ASATVRQRPI DAATDCDPRA CYDSFCKHWQ
QAHEIIQHAG PPTHDDVLGV VSHLDYMVTL LLVELHHCNK VSLPTADAAP PTAPCLEYLL
SENLLDKLYE WASTTGRYAN AVRLEQLKLY ELLVSHSRHQ LLCHEPFLRP LLKILASSQG
EIFPPDLEKR LVILLNQLCV VLMQNVHLLD LFFFSAQTQV QEQIQNGSLA APKSGTTTNF
IIFSLLIPYV HREGSLGHQA RDALLLCMAL SQKNSNIGHY IAQYSSICPL LVTGLGGLYS
RLPNSIEVSA IDWHRITPDD VAEIPELTLF MNALEFCNAV VQVAHEMIKQ QLLDFMYQGF
IVPVLGPAIL QTLKGKHFQT NIDSQISAMS YLDLILRSIT EPGLMRAFVK FLLDTEKFDG
ERILDALVER LHSPDANLCM VTMALFDTLL GLHCEDLMLE LLLKYMLPGK HVPISHRHKI
NKIDPYLNTT EFFLELTPDV MKRARDLARP KSVHELVDPG AALSSTMLPS LPSPVMSKTI
GANWNYYGHY TGDSLYANIQ AYLFEAHSRI AQCQRDCGKW ANNYRYQKWP RQGQVRATSH
ALELARQFFS EFGTATPVAV AAVASSELGE KQLDSLQSIG ESSGYESFKW RPDDADANDA
TTTTATSDPD VEHNNSSNHN NSSINSSGRR DLWRVSHSAR NEILLTDLDF SEDLFAQGTV
NLGPFLNAIW GKLQTFTSNS LYVNLHLTGL ITRLAWYPLP LIHSLLLRSD IAITSDTPSF
HQVLRMLKQQ IDAELPVAEN SLEIIDVARS SLIDREFRLI NARKVSDNSP LHQQHHQQQQ
LQHTTNSTHQ QQQAQQRSTY ATLSAATPMH ATPTSAYDPF RRSDNKRRSI SASISNIFGR
KSTSSTAAAN PNPASSGLSQ IYAFFTGAAS TLVGGINGEV NSRGVAQENP RGNTCETSLS
TTPRLDAQAT SASSTNSSIG GSTQTLSATH SSSTLHGVES GPQTASFNSE PVSMDSVASM
GIIANTSGTE RSRDLALCAV LLDEWLKELA AIALEQSVVL VTEQLL