U518_DROMO
ID U518_DROMO Reviewed; 1066 AA.
AC B4KJS5;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 45.
DE RecName: Full=FHIP family protein GI14169;
GN ORFNames=GI14169;
OS Drosophila mojavensis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7230;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15081-1352.22;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SIMILARITY: Belongs to the FHIP family. {ECO:0000305}.
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DR EMBL; CH933807; EDW11520.1; -; Genomic_DNA.
DR RefSeq; XP_002002078.2; XM_002002042.2.
DR AlphaFoldDB; B4KJS5; -.
DR STRING; 7230.FBpp0163386; -.
DR EnsemblMetazoa; FBtr0164894; FBpp0163386; FBgn0136922.
DR GeneID; 6576075; -.
DR eggNOG; KOG3695; Eukaryota.
DR HOGENOM; CLU_007807_0_0_1; -.
DR InParanoid; B4KJS5; -.
DR OMA; CLDWDSG; -.
DR PhylomeDB; B4KJS5; -.
DR Proteomes; UP000009192; Unassembled WGS sequence.
DR InterPro; IPR019384; FHIP.
DR InterPro; IPR045669; FHIP_C.
DR InterPro; IPR045668; FHIP_KELAA_motif.
DR PANTHER; PTHR21705; PTHR21705; 1.
DR Pfam; PF19314; DUF5917; 1.
DR Pfam; PF19311; KELAA; 1.
DR Pfam; PF10257; RAI16-like; 1.
PE 3: Inferred from homology;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..1066
FT /note="FHIP family protein GI14169"
FT /id="PRO_0000379010"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 651..682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 821..913
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 935..1007
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 652..682
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 821..878
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..913
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 946..1007
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 500
FT /note="Phosphoserine"
FT /evidence="ECO:0000250"
FT MOD_RES 820
FT /note="Phosphoserine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 1066 AA; 117622 MW; AE9E59C05A0D4251 CRC64;
MSWLRTSPLR QSLTRSGSSS GNGSSGTATT MRQRPIDAAT DCDPRACYDS FCKHWQQAHE
IIQHPGTPTH DDVLGVVSHL DYMVTLLLVE LHHCNKVSLP SADAAPPAAP CLEYLLSENL
LDKLYEWASS TGRYANAVRL EQLKLYELLV SHSRHQLLCH EPFLRPLLKI LASSQGEIFP
PDLEKRLVIL LNQLCVVLMQ NVHLLDLFFF SAQTQVQEQI QNGSLPAPKS GTTTNFIIFS
LLIPYVHREG SLGHQARDAL LLCMALSQKN SNIGHYIAQY SSICPLLVTG LGGLYSRLPN
SIEINSIDWH RITPDDVTEI PELTLFMNAL EFCNAVVQVA HEMIKQQLLD FMYQGFIVPV
LGPAILQTNI DSQISAMSYL DLILRSITEP GLMRAFVKFL LDTEKFDGER ILDALVERLH
SPDANLCMVT MALFDTLLGL HCEDLMLELL LKYMLPGKHV PISHRHKINK IDPYLNTTEF
FLELTPDVMK RARDLARPKS VQELVDPAAT ATTTATAPSM LLSLPSPVMS KTIGANWNYY
GHYTGDSLYA NVQAYLFEAH SRIAQCQRDC RKWANSYRYQ KWPRQGQARA TAHALELARQ
FFSEFGTAAP VVAAPVASEA GEKQLDSLQS IGESSGYESF KWRPADEDAE GIDVTTTTTA
SASDTDLEHN NNSSSISSGR RDSWRISHSS RNEILLTDLD FSEDLFAQGT VSLGPFLNAI
WSKLQTFTSN SLYVNLHLTG LITRLAWYPL PLIHSLLLRS DIAITSDTPS FHQVLRMLKQ
QIDAELPVAE NSLEIIDVAR SYLIDREFRL VNARKITDNS PLHQQLQHQQ QHQQLAQTNS
HTQQQQQQQQ QQAQQRSTYA TLSAATPVQA SPTSAYDPFR RSDNKRRSIS RSITSMFSRR
STSSTPASNG NSASSGLSQI YAFFTGAAST LVGGSGGEGS GARGAAQDST RGNTCETSLS
TAPRQEPQTN VGSSSNSSIG SSTQTLSGTH SSSTLHGVES GLQTGNFNSE PVSLDSVASM
GIIANTSGTE RSRDLALCAV LLDEWLKELA AVALEQSVVL VTEQLL