U518_DROPE
ID U518_DROPE Reviewed; 1067 AA.
AC B4G8N3;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 42.
DE RecName: Full=FHIP family protein GL19323;
GN ORFNames=GL19323;
OS Drosophila persimilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7234;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSH-3 / Tucson 14011-0111.49;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SIMILARITY: Belongs to the FHIP family. {ECO:0000305}.
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DR EMBL; CH479180; EDW28713.1; -; Genomic_DNA.
DR RefSeq; XP_002014717.1; XM_002014681.1.
DR AlphaFoldDB; B4G8N3; -.
DR STRING; 7234.FBpp0183430; -.
DR EnsemblMetazoa; FBtr0184938; FBpp0183430; FBgn0156922.
DR GeneID; 6589774; -.
DR KEGG; dpe:6589774; -.
DR eggNOG; KOG3695; Eukaryota.
DR HOGENOM; CLU_007807_0_0_1; -.
DR OMA; CLDWDSG; -.
DR PhylomeDB; B4G8N3; -.
DR Proteomes; UP000008744; Unassembled WGS sequence.
DR InterPro; IPR019384; FHIP.
DR InterPro; IPR045669; FHIP_C.
DR InterPro; IPR045668; FHIP_KELAA_motif.
DR PANTHER; PTHR21705; PTHR21705; 1.
DR Pfam; PF19314; DUF5917; 1.
DR Pfam; PF19311; KELAA; 1.
DR Pfam; PF10257; RAI16-like; 1.
PE 3: Inferred from homology;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..1067
FT /note="FHIP family protein GL19323"
FT /id="PRO_0000379011"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 503..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 832..1013
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 837..881
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 892..1013
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 508
FT /note="Phosphoserine"
FT /evidence="ECO:0000250"
FT MOD_RES 835
FT /note="Phosphoserine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 1067 AA; 116893 MW; 3BDFCCBF9C796160 CRC64;
MSWLRSSPLR QSGNGGGGGV STGHSSTGSL RQRPIDAATD CDPRACYDSF CKHWQQAYDI
IQHYAPPTHD DVLGVVSHLD YMVTLLLVEL HHCNKVSLPS TDASAAPAAP CLEYLLSENL
LDKLYEWACT TGRYANAVRL EQLKLYELLV SHSRHQLLCH EPFLRPLLKI LASSQGEIFP
PDLEKRLVIL LNQLCVVLMQ NVHLLDLFFF SAQTQVQEQI QNGNVPPPKS GTTTNFIIFS
LLIPYVHREG SLGHQARDAL LLCMALSQKN SNIGTYIAQY SSICPLLVTG LGGLYSRLPN
SIEISSIDWH RITPDDVTEI PELTLFMNAL EFCNAVVQVA HEMIKQQLLD FMYQGFIVPV
LGPAVLQTLK GKHFQTNIDS QISAMSYLDL ILRSITEPGL LRAFVKFLLD TEKFDGERIL
DSLVERLNSP DANLCMVTMA LFDTLLGLHC EDLMLELLLK FMLPGKHVPI SHRHKINKID
PYLNSSDFFL ELSPDVLKRA RDLARPKSVH EQQPPSGATG EQPIQPLAWP SLPSPVMSKT
IGANWNYYGL HTGDSLYANL QAYLFEAHWR IAQCQRDCLK WANSYRYQKW PRHGQARVHA
HALELARQFF SEFGGGPPAI ASESAGEKQL DSLQSIGESS GYESFKWRPA DEESDATDLT
VTTTTTTASE ADLEHNSSSI SSGMGGGGGA AAGRRGEAWR ISHTNRNELL LTDLDFSEDL
FAQGTVSLGP FLNAIWGKLQ TFTSNSLYVN LHLTGLITRL AWYPLPLIHS LLLRSDIAIT
SDTPSFHQVL RILKQQIDAE LPVTEDSLEI IDVARSSLID REFRLVNARK GNENSPLHHH
QQPQTTLSQQ QQQQQGQQRS AYATLSAATP VQATQTSAYD PFKRSDNKRK SISKSISSMF
SRRSTPNPPS SAGAASTLVG NNNSGSGQSQ PFSSTGTGTC ETSLSTNPQS GAAAARSTGT
ATTANGNSSN SNISIGGSTQ TLSGHSNTTT YSSSTLHGLD GGPQTGSFNS EPASLDSVAS
MGIIASTSGT ERTRDVALCA VLLDEWLKEL AAIAQEQSVV LVTDQLL