ID   U518_DROWI              Reviewed;        1097 AA.
AC   B4MTY2;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=FHIP family protein GK23746;
GN   ORFNames=GK23746;
OS   Drosophila willistoni (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7260;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14030-0811.24;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the FHIP family. {ECO:0000305}.
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DR   EMBL; CH963852; EDW75571.1; -; Genomic_DNA.
DR   RefSeq; XP_002064585.1; XM_002064549.2.
DR   AlphaFoldDB; B4MTY2; -.
DR   STRING; 7260.FBpp0252889; -.
DR   PRIDE; B4MTY2; -.
DR   EnsemblMetazoa; FBtr0254397; FBpp0252889; FBgn0225708.
DR   GeneID; 6641579; -.
DR   KEGG; dwi:6641579; -.
DR   eggNOG; KOG3695; Eukaryota.
DR   HOGENOM; CLU_007807_0_0_1; -.
DR   InParanoid; B4MTY2; -.
DR   OMA; CLDWDSG; -.
DR   PhylomeDB; B4MTY2; -.
DR   Proteomes; UP000007798; Unassembled WGS sequence.
DR   InterPro; IPR019384; FHIP.
DR   InterPro; IPR045669; FHIP_C.
DR   InterPro; IPR045668; FHIP_KELAA_motif.
DR   PANTHER; PTHR21705; PTHR21705; 1.
DR   Pfam; PF19314; DUF5917; 1.
DR   Pfam; PF19311; KELAA; 1.
DR   Pfam; PF10257; RAI16-like; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..1097
FT                   /note="FHIP family protein GK23746"
FT                   /id="PRO_0000379014"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          639..684
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          820..856
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          932..1042
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..24
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        667..684
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        820..835
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        932..1025
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         491
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         823
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   1097 AA;  120109 MW;  44C04D1A6250BAB6 CRC64;
     MSWLRSSPLR QSLTRTTSSG NGIRPIDAAT DCDPRACYDS FCKHWQQAYD IIQHSSAPAP
     THDDVLGVVS HLDYMVTLLL VELHNCNKIS LADSNAPPTA PCLEYLLSEN LLDKLYEWAA
     TTGRYANAVR LEQLKLYELL VSHSRHQLLC HEPFLRPLLK ILASSQGEIF PPDLEKRLVI
     LLNQLCVVLM QNVHLLDLFF FSAQTQVQEQ IQNGNVPPPK SGTTTNFIIF SLLIPYVHRE
     GSIGHQARDA LLLCMALSQK NSNIGTYIAQ YSSICPLLVT GLGGLYSRLP NSIEINSIDW
     HRITPDDVTE IPELNLFMNA LEFCNAVVQV AHEMIKQQLL DFMYQGFIVP VLGPAILQTN
     IDSQISAMSY LDLILRSITE PGLLRAFVKF LLDTEKFDGE RILDALVERL NSPDGNLCMV
     TMALFDTLLG LHCEDLMLEL MLKYMLPGKH VPISHRHKIN KIDPYLNSTE FFLELTPDVM
     KRARDLARPK SVNEHQQESA LPNELSLPSL PSPVMSKTIG ANWNYYGLHT GDSLYANLQA
     YLFEAHWRIA QCQRDCLKWA NSYRYQKWPR QGQPQNRLHN HALELAKQFF IEFGGEGIGG
     LGGGAAIASE AGEKQLDSLQ SIGESSGYES FKWRPADEDV SASSGNGTGS VVVGDHPGHD
     VTISESDVDG HNISSSLSNS SGRRESWRIS HNTRNELLLT DLDFSEDLFA QGTVSLGPFL
     NAIWGKLQTF TSNSLYVNLH LTGLITRLAW YPLPLIHSLL LRSDIVITSD TPSFHQVLRI
     LKQQIDAELP VTEDSLEIID VARSSLIDRE FRLVNARKGN ENSPLHQQQS LQHPHHLQPL
     PAPQQTGAGA QQRSAYATLS AATPVQATPF SAYDPFKRSN NSRRSISKSI TSMFSRKSTL
     PAPAIAPTPA SSGLSQIYAF FTGAASTIMG NNNQQSSNQT HLNSSSSSAV TTCETSLSTQ
     PHATGPGSAQ LRTTSSTIST SSGTTAGSGG GGGSGSNSSF SIGGSTQTLS AHSNNTTNSS
     STLHGGLDGI GPPTGSFNSE PVSLDSVGSS MGIIANTSGT ERSRDLALCA VLLDEWLKEL
     AAIAQEQSIV LVTDQWL